Erratum: Analytical Sciences, 2016, Vol. 32, No. 2, p. 167, Simultaneous Quantification of Iodine and Other Elements in Infant Formula by ICP-MS Following an Acid Digestion with Nitric Acid and Hydrogen Peroxide.

On page 168, the left column, line 26 to 29, the sentence,Working standard solutions (1, 5, 7.5, and 10 ng mL(-1)) were prepared from the iodine stock solution by dilution with 7.0% (v v(-1)) nitric acid, 5.0% (v v(-1)) acetic acid and 1.2% (v v(-1)) hydrogen peroxide.should readWorking standard solutions (1, 5, 7.5, and 10 ng mL(-1)) were prepared from the iodine stock solution by dilution with 7.0% (v v(-1)) nitric acid and 5.0% (v v(-1)) acetic acid.

Simultaneous Quantification of Iodine and Other Elements in Infant Formula by ICP-MS Following an Acid Digestion with Nitric Acid and Hydrogen Peroxide.

A method for quantifying iodine in infant formula is described. Nitric acid and hydrogen peroxide converted iodine into iodate in microwave-assisted digestion and prevented iodine volatilization and memory effects. Acetic acid as a carbon source was added to both the sample and standard solutions as a countermeasure against carbon charge transfer to iodine and the addition of acetic acid helped to enhance the sensitivity. The instrument limit of quantification was 0.1 ng mL(-1) and the relative standard deviation was less than 3%. The spike recoveries were between 94.8 and 106%. Good agreement with the values obtained using the tetramethylammonium hydroxide method was obtained for infant formula sold in several countries. This method permitted the simultaneous determination of iodine and 12 other important elements (Na, Mg, P, K, Ca, Cr, Mn, Fe, Cu, Zn, Se and Mo) in infant formula.

Effects of bovine alpha-lactalbumin on gastric defense mechanisms in naive rats.

We recently investigated the effects of the major proteins in cow's milk on gastric mucosal injuries in rat ulcer models. We found that alpha-lactalbumin (alpha-LA) has marked preventive effects against gastric mucosal injuries and that prostaglandin (PG) synthesis may contribute to these effects [Matsumoto et al., Biosci. Biotechnol. Biochem., 65, 1104-1111, 2001]. In this study, we investigated the effects of alpha-LA on several defense mechanisms of gastric mucosa by evaluating gastric PGE2 content, gastric mucin content, gastric luminal pH, gastric fluid volume, and gastric emptying in naive rats. Oral administration of alpha-LA (200, 500, and 1000 mg/kg) elevated endogenous PGE2 levels in gastric tissue and increased the gastric mucin contents of both the gastric fluid and the adherent mucus gel layer. In addition to these PG-related responses, alpha-LA also caused PG-independent responses such as elevation of gastric luminal pH, increase in gastric fluid volume, and delay in gastric emptying. These responses were observed to be dose-dependent (200-1000 mg/kg of alpha-LA). Thus, we demonstrated that alpha-LA enhances both PG-dependent and PG-independent gastric defense mechanisms in naive rats. Both of these mechanisms are probably involved in its gastroprotective action.