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Bioorg Med Chem Lett
; 12(21): 3033-6, 2002 Nov 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12372495
RESUMO
An efficient and practical method was established for solid-phase parallel synthesis of the peptide-bearing carboxamide derivatives of chloroorienticin B, and over 80 compounds were synthesized simultaneously. Among the derivatives prepared, compounds having both tryptophan and tyrosine residues (1-3) were found to possess potent antibacterial activity against VRE.