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1.
Heliyon ; 7(3): e06581, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33869833

RESUMO

The paper focuses on the methods of linguistic analysis in the sphere of teaching foreign languages as a form of shaping students' identity. By putting forward the hypothesis that proper language acquisition should be based on fundamental cultural values and their adequate linguistic interpretation, we propose the pragmatic and axiological linguistic modelling as an indispensable FLT tool, develop its methodology and prove its future validity on the material of FLT discourse. The research gives a step-by-step explanation of how to implement this modelling through discourse analysis, pragmatic-communicative analysis, functional and linguoaxiological analysis. This procedure foregrounds dominant axiological spheres through the process of constructing value-charged concepts of the professional FLT discourse. From the standpoint of generating FLT material, the method helps to reflect most important professional processes and purposefully form students' professional competences necessary in the sphere.

2.
Heliyon ; 6(12): e05763, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33409385

RESUMO

The aim of this research paper is to reveal and explore the negative concepts, i.e. anti-values, verbalized in the professionally compiled media texts on the topic of YouTube as they shape the idea of what YouTube is and how it functions. The authors identify anti-values in the newspaper and magazine articles, reveal linguistic means through which they are implemented, as well as define their relationship with the context. The authors attempt to rationalize the use of anti-values in the texts about YouTube and provide a commentary on both linguistic and extra-linguistic features of these entities. Anti-values reflect concepts, phenomena, ideas or notions that are deemed unacceptable or undesirable in some cases universally, and in some specifically by the users of the platform or those affected by it. The research findings can be used in both axiological and socio-linguistic studies conducted for pragmatic, scientific or educational purposes.

3.
Heliyon ; 5(12): e02988, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31872136

RESUMO

Drawing on the studies of linguistics, axiology and discourse analysis, this paper contributes to the linguistic framework of value-based communication studies by establishing the algorithm of shaping values in popular science IT discourse via the set of linguo-axiological methods. The authors' aims include establishing dominating communicative strategies employed by the authors of the texts; identifying language structures and lexical means responsible for the both explicit and implicit formation and verbalization of certain values represented in the texts about YouTube; organizing the identified values into a system as presented by the authors of the texts. The paper uncovers dominant YouTube text characteristics, focusing on the instrumental role of values this type of discourse represents, and implements a complex methodological set (CDA and linguo-axiological analysis) in order to outline three basic communicative strategies that the authors of the texts employ: the information strategy; the instruction strategy; the evaluation strategy. The conducted research reveals that the texts of mass media about YouTube contain the following values, classified by the authors into three axiological groups: relevance (approval, authenticity, entertainment, fame, influence, popularity); relationship (accessibility, connection, feedback, relatability); profession (career, competitiveness, money, promotion, time). The results of the study include theoretical conclusions about how the modern-day discourse of information technology (IT-discourse) reflects both fundamental and profession-specific human values, thus shaping the way addressees perceive the industry through language. These findings make it possible to form a new type of IT-discourse text architecture, which would take into account the pragmatic-axiological charge necessary to shape and divert the set of addressees' values.

4.
Pathophysiology ; 25(1): 13-17, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29033135

RESUMO

An increase in growth rates of children suffering from growth hormone deficiency (GHD) subjected to recombinant growth hormone treatment (rGHT) was shown to be accompanied by acceleration of metabolic processes that may stimulate oxygen consumption in various organs and tissues. Therefore, oxygen-transporting properties of RBC should undergo considerable changes during the rGHT. The aim of this study was to examine the effects of rGHT on erythrocyte shape and hemoglobin state in GHD children. The level of oxyhemoglobin (Oxy-Hb) in RBC was analyzed by Raman spectroscopy. The RBC count, mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV) and other parameters were calculated. The blood of eleven treatment-naive prepubertal children with GHD (aged 3-9, median 5.7 years) was examined and compared with control group (aged 5-7; median 6.0 years) at three time points: 0, 3 and 12 months of rGHT. Before rGHT, the MI in GHD children was higher (median 0.48 vs 0.14 p=0.0018) and the RBC count was lower (median 4.20 vs 4.96 1012 cells/L p=0.0022) than in control group. After the treatment, cell count in GHD patients did not differ significantly from the control group, but Oxy-Hb level became higher (median 0.64 vs 0.41 p=0.0075). During rGHT, MCV decreased (median 80.3 vs 83.2µm3 p=0.0231). Morphological and functional characteristics of erythrocytes in GHD children were shown to differ significantly from the healthy control group. A twelve-month rGHT partially improved some of the studied parameters but Oxy-Hb level and echinocyte count remained high.

5.
PeerJ ; 3: e1055, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26137433

RESUMO

The aim of our study was to examine the effects of 12-month therapy with recombinant growth hormone (rGH) on the blood antioxidant system in children with growth hormone deficiency (GHD). Total antioxidant capacity (TAC) of plasma was measured by FRAP (ferric reducing antioxidant power or ferric reducing ability of plasma); activities of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes were assessed; non-protein thiols (NT) and ceruloplasmin (CP) levels were also measured. These parameters were determined before and after 12 month of rGH treatment. Eleven treatment-naive prepubertal children with growth hormone deficiency were included in the study. Another 11 prepubertal children comprised a control group. Before rGH treatment, TAC of plasma and NT level in the control group were significantly lower (726 ± 196 vs. 525 ± 166 µmol/L, P = 0.0182 and 0.92 ± 0.18 vs. 0.70 ± 0.22 µmol/ml, P = 0.0319, before and after the therapy, respectively). The only parameter that significantly (19.6 ± 4.7 vs. 14.5 ± 3.4 Units/g Hb, P = 0.0396) exceeded the same in the control group after rGH therapy was SOD activity. However, none of the measured parameters of antioxidant system in GHD children, except for TAC (525 ± 166 vs. 658 ± 115 µmol/L, P = 0.0205), exhibited significant improvement toward the end of the 12-month treatment period, although non-significant changes in CAT activity and CP level were also observed. This work has demonstrated that some parameters of the blood antioxidant system are out of balance and even impaired in GHD children. A 12-month treatment with rGH resulted in a partial improvement of the antioxidant system.

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