RESUMO
AIM: Analyze the state of population immunity to polioviruses in children population of 14 administrative territories of the Russian Federation. MATERIALS AND METHODS: Antibody titers against reference vaccine poliovirus serotypes 1, 2 and 3 were determined by using neutralization reaction in cell culture Hep-2. RESULTS: Several years after the termination of conduction of National immunizations days the percent of seronegative children was shown to increase, especially to poliovirus serotype 3, in most of the territories. Possible reasons for fluctuation of geometric mean antibody titers against polioviruses in children in various territories as well as in various years in the same territory were established. CONCLUSION: Quality vaccine prophylaxis and control of population immunity state among children population play an important role in the maintenance of Russian Federation status as a country is free from poliomyelitis.
