RESUMO
Preleukemia, which can only be diagnosed retrospectively with certainty, presents multiple findings and clinical data which contribute to a pattern recognition process. The development of cytogenetic and marrow culture studies has not only provided additional criteria for diagnosis but also better indices of prognosis. Preleukemia can be considered to be an early expression of neoplastic disease that merges into smoldering leukemia and progresses to acute leukemia. However, in the prospective evaluation of a patient, the term hemopoietic dysplasia should be used since there are no criteria to predict the outcome in an individual case.
Assuntos
Pré-Leucemia/diagnóstico , Doença Aguda , Medula Óssea/patologia , Aberrações Cromossômicas , Diagnóstico Diferencial , Humanos , Leucemia/etiologia , Pré-Leucemia/genética , Pré-Leucemia/patologia , Prognóstico , Estudos RetrospectivosRESUMO
The scanning electron microscopy of synovial membrane from the radiocarpal and intercarpal joints near the lateral and medial borders of the tendon of the extensor carpi radialis muscle was studied in 5 ponies. Three different morphologic types of synovial membrane were observed. Type 1 synovial membrane was folded and had a surface mat of fibers separated by 1- to 5-micron-diameter holes. The 2nd and 3rd types of synovial membrane were both villous. The surface of type 2 synovial membrane was fibrillar but the surface of type 3 synovial membrane was cellular. The type of synovial membrane present was related to the function of the joint capsule region rather than to the type of subintimal connective tissue. Normal equine synovial membrane was found to be more villous in some regions of the joint capsule than synovial membrane of other species.
