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Hinyokika Kiyo ; 67(4): 167-170, 2021 Apr.
Artigo em Japonês | MEDLINE | ID: mdl-34107614

RESUMO

A 62-year-old man was treated for castration-resistant prostate cancer (CRPC) ; however, his condition progressed. The patient planned to visit our department for treatment, including palliative care. However, he visited the emergency room with a complaint of a persistent nose bleed just before visiting our department. He had an active nose bleed, disseminated intravascular coagulation (DIC), and leukoerythroblastosis upon admission. After hospitalization, we performed a bone marrow puncture and biopsy to investigate the cause of the DIC, which revealed a dry tap and hypoplastic bone marrow. This was believed to be due to the progression of CRPC. He developed wheals upon receiving repeated platelet transfusions for the DIC. Although we administered antihistamine and steroids to control these side effects, he additionally developed chills and fever. Because of the difficulty in controlling side effects, we decided to use washed platelets. Thereafter, blood transfusions of washed platelets were performed without the occurrence of side effects. However, the patient died because of the worsening of his condition.


Assuntos
Coagulação Intravascular Disseminada , Neoplasias de Próstata Resistentes à Castração , Coagulação Intravascular Disseminada/etiologia , Coagulação Intravascular Disseminada/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Transfusão de Plaquetas , Neoplasias de Próstata Resistentes à Castração/tratamento farmacológico
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