RESUMO
Autotransfusion of hemosorbent-treated blood was used as a method of stimulation of reparative regeneration processes in 52 patients with continuously non-healing gastric ulcers. In 35 patients (67%) the ulcers cicatrized during the first 2 weeks of the posttransfusion period. The investigation of the enzymatic status of neutrophils showed that autotransfusion of sorbent blood raised the functional activity of neutrophils and the cation protein level in them which could promote the cleansing of the ulcer surface from necrotic masses and intensify processes of cicatrization.
Assuntos
Transfusão de Sangue Autóloga , Hemoperfusão , Neutrófilos/enzimologia , Úlcera Gástrica/terapia , Fosfatase Ácida/sangue , Adulto , Fosfatase Alcalina/sangue , Hidrolases de Éster Carboxílico/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Peroxidases/sangue , Úlcera Gástrica/sangue , CicatrizaçãoRESUMO
The results of the histological and electron microscopic investigation of adipose and reticular cells and their interconnections with blood cells are presented in the material of trephine biopsies of the iliac bone. A possibility for development of adipocytes from the adventitial reticular cells is demonstrated. Close contacts are revealed between pre-adipocytes and young hemopoietic cells. Two types of the reticular cells are characterized, they differ in their position, structural organization and interconnection with the young hemopoietic elements. The peculiarities revealed in the morphofunctional state of the microenvironmental structures demonstrate functional variegation of the stromal elements, and also attest an essential importance of intercellular contacts of the hemopoietic predecessors and the stromal cells in maintaining the hemopoietic function of the bone marrow.
Assuntos
Tecido Adiposo/citologia , Células da Medula Óssea , Ílio/citologia , Reticulócitos/citologia , Adulto , Biópsia , Contagem de Células , Hematopoese , Células-Tronco Hematopoéticas/citologia , Humanos , Junções Intercelulares/ultraestrutura , Microscopia EletrônicaRESUMO
Results of histological and ultramicroscopic investigations of sinusoid vessels are presented. Interrupted structure of the basal membrane and continuous endothelial lining are revealed. Endotheliocytes of two types are described. At places of blood cells migration functional activity of endothelium is increased and the basal membrane is absent. A suggestion is made that the endothelial cells directly influence hemopoiesis.