[Use of WOBE-MUGOS E for prevention and correction of experimental doxorubicin side-effects]. / Ispol'zovanie VOBE-MUGOS E dlia profilaktiki i korrektsii pobochnykh reaktsii doksorubitsina gidrokhlorida v éksperimente.

Examined in treating rats with Guerin's carcinoma with doxorubicin was the possibility that the polyenzymic drug preparation wobe-mugos E had hepatoprotective, cardioprotective and myeloprotective effects. In intramuscular administration wobe-mugos E has not been found to stimulate the tumour growth, it exhibited a manifest hepatoprotective and myeloprotective actions with respect to adverse reactions of doxorubicin but failed to diminish cardiotoxicity of the latter. The protective effect of the above polyenzymic drug was of a dose-dependent character.