[The treatment of leptospirosis complicated by severe liver-kidney failure]. / Lechenie leptospiroza, oslozhnennogo tiazheloi pechenochno-pochechnoi nedostatochnost'iu.

The authors examined 16 patients with severe forms of leptospirosis complicated by hepato-renal insufficiency. The treatment program included the following methods: hemodialysis, hemosorption, intraportal administration of drugs, gastrointestinal sorption via a heterospleen, hyperbaric oxygenation. As a result of this complex treatment lethality decreased by 15%.

[The correction of functional disorders of the cardiovascular system in patients with acute kidney failure treated by hemodialysis]. / Korrektsiia funktsional'nykh narushenii serdechno-sosudistoi sistemy u bol'nykh s ostroi pochechnoi nedostatochnost'iu, lechennykh gemodializom.

A study is presented of the central hemodynamics in 38 patients with severe forms of acute renal failure of different genesis. Disorders were revealed related both to renal failure and use of active methods of extracorporal detoxication, namely, hemodialysis and hemosorption. Measures on the correction of disorders of the central hemodynamics are described.

[Detoxication in the critical state due to rhabdomyolysis]. / Detoksikatsiia pri kriticheskom sostoianii, obuslovlennom rabdomiolizom.

An examination of 92 patients with the crush syndrome and the position compression syndrome was made. All the patients were examined by clinico-biochemical methods, the cardiovascular system being also studied. The leading place is occupied by endogenous intoxication. The metabolic disorders were of a total character involving different links of metabolism. It required inclusion of efferent methods in the program of treatment. The most effective program of using efferent methods of treatment was developed on the basis of the state of hemodynamics and clinico-biochemical peculiarities.

[A clinico-experimental study of lymphogenous detoxification in acute renal and kidney insufficiency]. / Kliniko-éksperimental'noe izuchenie limfogennoi detoksikatsii pri ostroi pochechno-pechenochnoi nedostatochnosti.

Lymphogenous methods for detoxification were employed in 23 patients with acute concurrent renal and hepatic failure of various etiology. Pronounced changes in the composition of lymph and moderate to severe hyperhydration are indications for combined application of lymphosorption (LS) and lymphodialysis (LD). The combined use of LS and LD makes it possible to reduce the number of required hemodialyses three times as much as that of hemodialysis alone and to make the time of a hemodialysis shorter by 1.5-2 hours.