RESUMO
Clinical and laboratory evaluation of pectins application efficacy demonstrated that the patients treated with pectines has lower frequency of bacteriemia, intoxication, infectious complications and lethality. Pectins use per os resulted by acceleration of burns wounds healing and by lower microbial dissemination. Frequency of coagulase-positive staphylococci, streptococci and enterococci isolation was also lower in the treated group of patients when compared to the control group. Feces microbial profile also demonstrated positive trend--normal microflora (bifidobacteria and lactobacilli) enhanced, opportunistic bacteria diminished. Pectins application provided normalization of leucocytes, lymphocytes, B-lymphocytes, immunoglobulins A and G. The results of investigation demonstrated pectins efficacy at the complex treatment regimes of the patients with burns.
Assuntos
Queimaduras/complicações , Pectinas/uso terapêutico , Sepse/tratamento farmacológico , Sepse/prevenção & controle , Adulto , Idoso , Formação de Anticorpos/efeitos dos fármacos , Queimaduras/mortalidade , Feminino , Humanos , Imunidade Celular/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Sepse/microbiologia , Sepse/mortalidade , Cicatrização/efeitos dos fármacosRESUMO
In this review the role of glutamine in enteral nutrition in intestinal insufficiency is shown. It is emphasized, that glutamine plays an important role in preservation of structure and function of intestines in normal state and under stressful condition.
Assuntos
Nutrição Enteral , Glutamina/farmacologia , Glutamina/fisiologia , Intestinos/efeitos dos fármacos , Animais , Células Cultivadas/efeitos dos fármacos , Dieta , Metabolismo Energético , Nutrição Enteral/efeitos adversos , Mucosa Gástrica/metabolismo , Mucosa Gástrica/fisiologia , Glutamina/administração & dosagem , Glutamina/metabolismo , Humanos , Mucosa Intestinal/metabolismo , Mucosa Intestinal/fisiologia , Intestinos/fisiologia , Rim/efeitos dos fármacos , Rim/metabolismo , Fígado/efeitos dos fármacos , Fígado/metabolismo , Músculo Esquelético/efeitos dos fármacos , Músculo Esquelético/metabolismo , Ratos , Estresse Fisiológico/metabolismo , Fatores de TempoRESUMO
The influence of food fibres and plant proteins on microorganisms, bacteriophages, antibiotics and penicillinase was studied in vitro. It was shown that pectin was the only agent that had a bactericidal effect on the most widely distributed pathogenic and opportunistic microorganisms and did not influence indigenic microflora. High concentrations of pectin (> 2 per cent) had an inactivating effect on therapeutic bacteriophages. There was also a decrease in the antimicrobial activity of penicillins. The other agents tested i.e. wheat bran, soya isolate and soybean flour had no influence on microorganisms, bacteriophages and antibiotics. No sorption activity of the food fibres and plant proteins with respect to microorganisms and antibiotics or their effect on penicillinase was observed.
Assuntos
Antibacterianos/farmacologia , Pectinas/farmacologia , Penicilinase/metabolismo , Penicilinas/farmacologia , Bactérias/efeitos dos fármacos , Bacteriófagos/efeitos dos fármacos , Fibras na Dieta/farmacologia , Antagonismo de Drogas , Interações Alimento-Droga , Proteínas de Plantas/farmacologia , Proteínas de Soja/farmacologiaRESUMO
An analysis of results of 26 patients has been made who had incompetent sutures of anastomoses and stump of the duodenum at the nearest postoperative period after gastric resection. In 14 patients (main group) aspiration-lavage method of drainage was used, in 12 patients (control group) other methods of treatment of incompetent sutures were employed. The advantage of the aspiration-lavage method of treatment over other methods is shown.
Assuntos
Duodeno/cirurgia , Gastrectomia , Deiscência da Ferida Operatória/cirurgia , Adulto , Idoso , Anastomose Cirúrgica , Emergências , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Peritonite/etiologia , Peritonite/mortalidade , Peritonite/cirurgia , Reoperação , Sucção/métodos , Deiscência da Ferida Operatória/complicações , Deiscência da Ferida Operatória/mortalidade , Irrigação Terapêutica/métodosRESUMO
The paper is concerned with analysis of the results of x-ray examination of 78 patients with enterocutaneous fistulas of various etiology and site. The authors have shown the characteristic features of x-ray examination of patients in whom the fistulas were at the acute phase of their development. They have also defined the diagnostic value of the employed methods and their efficacy for the diagnosis not only of fistulas but also of related complications (inflammatory infiltrates and abscesses of the abdominal cavity, fatty phlegmon, purulent "fillings", complicated fistulas, etc.). During combined x-ray investigation accurate diagnosis of fistulas was established in 97.4% of the patients, purulent complications were revealed in 94.6%.