RESUMO
Long-term observation of workers engaged into production of VX chemical diagnosed slow progressing manifestation of chronic occupational poisoning with the chemical. The characteristic nervous, digestive, locomotory, visual and cardiovascular symptoms were revealed. The authors presented laboratory and instrumental data on the cases. As the treatment appeared ineffective, further adjustment and improvement of the therapy is required. The article demonstrated the main underlying metabolic disorders that could be addressed by the pathogenetic therapy.
Assuntos
Indústria Química , Substâncias para a Guerra Química/intoxicação , Inibidores da Colinesterase/intoxicação , Doenças Profissionais/induzido quimicamente , Compostos Organotiofosforados/intoxicação , Adulto , Doença Crônica , Humanos , Pessoa de Meia-Idade , Ocupações , Fatores de TempoAssuntos
Bronquite/terapia , Intubação Intratraqueal , Laringite/terapia , Traqueíte/terapia , Doença Aguda , Pré-Escolar , Humanos , LactenteRESUMO
The structure of the duodenum mucosa and proliferation of the epithelium were studied in 138 patients with chronic hepatitis and cirrhosis of the liver by count of the number of mitoses and that of cells labeled in the phase of DNA synthesis with 3H-thymidine. The atrophic changes revealed in the mucosa were noted together with the drop in the number of mitoses and the 3H-thymidine-labeled cells. This makes it possible to explain atrophy of the duodenum mucosa by inhibition of proliferative processes in the crypts.