[The effect of finoptin on platelet aggregation, blood coagulability and fibrinolysis in patients with ischemic heart disease during physical exercise]. / Vliianie finoptina na agregatsiiu trombotsitov, svertyvaemoct' krovi i fibrinoliz u bol'nykh ishimicheskoi bolezn'iu serdtsa pri fizicheskoi nagruzke.

Exercise platelet aggregation, blood coagulability, and fibrinolysis were examined in patients prior myocardial infarction 2-3 months following the disease. Seventy patients of whom 35 had received placebo and 35 finoptin prior to exercise were studied. The platelet aggregation, blood coagulability, and fibrinolysis were explored before and after bicycle ergometric test. Following exercise, the patients on placebo showed higher platelet aggregation, blood coagulability and lower fibrinolysis, whereas those on finoption exhibited a lower increase in platelet aggregation and blood coagulability and activated fibrinolysis.

[The coagulating and anticoagulating blood systems and thrombocyte aggregation in healthy subjects and patients with ischemic heart disease at rest and under physical loading]. / Svertyvaiushchaia, protivosvertyvaiushchaia sistemy krovi i agregatsiia trombotsitov u zdorovykh lits i bol'nykh ishemicheskoi bolezn'iu serdtsa v pokoe i pri fizicheskoi nagruzke.

A study was made of hemostasis, fibrinolysis and platelet aggregation at rest and exercise in 32 healthy persons and 35 patients suffering from coronary heart disease (CHD) with a history of myocardial infarction that had occurred 2-3 months before. It has been discovered as a result that in healthy persons at exercise, the blood coagulation system and fibrinolysis are activated, the level of antithrombin-III rises and initial platelet aggregation decreases. In patients with CHD at exercise, hypercoagulation, deceleration of fibrinolysis, and the decline of the level of AT-III are detectable, with platelet aggregation being enhanced.