Assuntos
Infarto do Miocárdio/sangue , Mioglobina/sangue , Doença Aguda , Angina Pectoris/sangue , Aspartato Aminotransferases/sangue , Ensaios Enzimáticos Clínicos , Doença das Coronárias/sangue , Creatina Quinase/sangue , Diagnóstico Diferencial , Humanos , Isoenzimas , L-Lactato Desidrogenase/sangue , Doenças Musculares/sangue , RadioimunoensaioRESUMO
Hormonal activity of the sera was studied immediately after blood collection and 6 months, one year and 1.5 years following their storage at a temperature of -20 to 25 degrees C in 10 healthy males aged 18 to 20 years. It was found that differently directed changes in immunologic activity of blood serum hormones took place on long-term storage at low temperatures. The data obtained suggest that the adrenocorticotropic hormone, immunoreactive insulin, protein-bound iodine and follicle-stimulating hormone retain the immunologic activity not more than one year, while the hormone, stimulating interstitial cells, thyrotrophic hormone, somatotrophic hormone, 17-HOCS, testosterone and aldosterone up to 1-1.5 years. During this storage of frozen biosubstrates the recurrent freezing out that produces changes in the immunologic activity of some hormones should be excluded.
Assuntos
Preservação de Sangue , Glucocorticoides/sangue , Insulina/sangue , Hormônios Adeno-Hipofisários/sangue , Testosterona/sangue , Adolescente , Adulto , Proteínas Sanguíneas/metabolismo , Humanos , Iodo/sangue , Masculino , Ligação Proteica , Refrigeração , Fatores de TempoRESUMO
A considerably increased content of adrenocorticotropic, somatotropic and thyreo-stimulating hormones of the hypophysis in the blood serum, as well as corticosteroids in the blood and especially in the day urine was noted in 27 male patients with the first 4--8 days after light mechanical traumas not resulting in pronounced disturbances of homeostasis and having favourable outcomes. It has been shown that a simultaneous assessment of cortisole and corticosterone in the day urine is most informative among the studied forms of adrenal hormones (17-OCS, cortisole, corticosterone) in the evaluation of the functional state of the adrenal cortex and corticosteroid balance in the organism of the patients.
Assuntos
Corticosteroides/análise , Hormônios Adeno-Hipofisários/análise , Ferimentos e Lesões/metabolismo , Adolescente , Adulto , Contusões/metabolismo , Fraturas Fechadas/metabolismo , Fraturas Expostas/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Ferimentos Penetrantes/metabolismoRESUMO
The efficacy of a specialized device for automatic ECG analysis was appraised on the grounds of examination of 1,499 healthy and sick persons. The method makes it possible to detect 74,2% of patients with diseases of the cardiovascular system. Patients with ischemic heart disease were detected with the greatest reliability (over 90%). A high reproduction of the results on homogeneous contingents of healthy and sick persons is shown, which is evidence that the use of specialized devices for automatic ECG analysis should be recommended for the cardiological screening of the population.
Assuntos
Diagnóstico por Computador/instrumentação , Eletrocardiografia/instrumentação , Cardiopatias/prevenção & controle , Programas de Rastreamento/instrumentação , Estudos de Avaliação como Assunto , Humanos , Federação RussaAssuntos
Hemostasia , Pneumonia/fisiopatologia , Doença Aguda , Adulto , Dipiridamol/uso terapêutico , Avaliação de Medicamentos , Fator XIII/análise , Produtos de Degradação da Fibrina e do Fibrinogênio/análise , Hemostasia/efeitos dos fármacos , Humanos , Masculino , Ácidos Nicotínicos/uso terapêutico , Pneumonia/tratamento farmacológicoAssuntos
Somatostatina , Adenoma/tratamento farmacológico , Animais , Diabetes Mellitus/tratamento farmacológico , Hormônios Gastrointestinais/metabolismo , Crescimento , Hormônios/uso terapêutico , Humanos , Hipotálamo/metabolismo , Ilhotas Pancreáticas/metabolismo , Neoplasias Pancreáticas/tratamento farmacológico , Úlcera Péptica/tratamento farmacológico , Adeno-Hipófise/metabolismo , Ratos , Somatostatina/fisiologia , Somatostatina/uso terapêuticoRESUMO
The following were studied in 24 healthy men aged from 20 to 40 years: circadian rhythm of catecholamines and their precursors production, 17-ketosteroids, 17-oxycorticosteroids, variational pulsometry indices, arterial pressure parameters, resilient-viscous properties of large arterial vessels and arterioles, indices characterizing the mechanical activity of the myocardium. Comparison of the results obtained indicated that, although there existed no complete correlation between these indices, there proved to be a nocturnal tendency to reduction of noradrenaline and dopamine production, to reduction of 17-ketosteroids and 17-oxycorticosteroids, along with rarefaction of cardiac contractions, increased variation in the rhythm, and diminution of arterial pressure and cardiac output parameters. Reverse changes were noted during the day-time.