RESUMO
The use of perfluoroorganic compounds, i.e. perfluorodecalin and "Perftoran", a blood substitute with the gas transfer function, known as "blue blood" (containing 3 vol. % of perfluoromethylcyclohexylpiperidin and 7 vol. % of perfluorodecalin as emulsion with the average particle size of 0.07 microns) in biotechnology for intensification of the Streptomyces purpurogeniscleroticus growth under submerged conditions was shown promising for the first time. An increase of the biomass output and higher yields of daunorubicin were also demonstrated.
Assuntos
Antibióticos Antineoplásicos/biossíntese , Daunorrubicina/biossíntese , Fluorocarbonos/farmacologia , Streptomyces/metabolismo , Meios de Cultura/química , Fluorocarbonos/química , Tamanho da Partícula , Streptomyces/efeitos dos fármacos , Streptomyces/crescimento & desenvolvimentoRESUMO
It was established that the application of deflectors lowers considerably the effectiveness of free ventilation. The contributors propose newly elaborated highly effective deflectors and demonstrate their cost saving applicability in industry.