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Proc Natl Acad Sci U S A ; 115(14): 3623-3627, 2018 04 03.
Artigo em Inglês | MEDLINE | ID: mdl-29555754

RESUMO

With over 3 billion airline passengers annually, the inflight transmission of infectious diseases is an important global health concern. Over a dozen cases of inflight transmission of serious infections have been documented, and air travel can serve as a conduit for the rapid spread of newly emerging infections and pandemics. Despite sensational media stories and anecdotes, the risks of transmission of respiratory viruses in an airplane cabin are unknown. Movements of passengers and crew may facilitate disease transmission. On 10 transcontinental US flights, we chronicled behaviors and movements of individuals in the economy cabin on single-aisle aircraft. We simulated transmission during flight based on these data. Our results indicate there is low probability of direct transmission to passengers not seated in close proximity to an infectious passenger. This data-driven, dynamic network transmission model of droplet-mediated respiratory disease is unique. To measure the true pathogen burden, our team collected 229 environmental samples during the flights. Although eight flights were during Influenza season, all qPCR assays for 18 common respiratory viruses were negative.


Assuntos
Movimentos do Ar , Viagem Aérea , Aeronaves , Doenças Transmissíveis/psicologia , Doenças Transmissíveis/transmissão , Atividades Humanas , Vírus/patogenicidade , Simulação por Computador , DNA Viral/análise , DNA Viral/genética , Saúde Global , Humanos , Medição de Risco , Vírus/classificação , Vírus/genética
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