1.
Structure
; 29(9): 935-936, 2021 09 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34478635
RESUMO
In this issue of Structure,Shang and Kojetin (2021) present insights into the binding mechanism of artificial agonists to the PPARγ nuclear receptor. These data support a two-step model with induced fit and conformational selection aspects. This mechanism may exist in related receptors, providing new opportunities for drug development.