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1.
Sensors (Basel) ; 21(21)2021 Nov 05.
Artigo em Inglês | MEDLINE | ID: mdl-34770678

RESUMO

With the rise in the employment of deep learning methods in safety-critical scenarios, interpretability is more essential than ever before. Although many different directions regarding interpretability have been explored for visual modalities, time series data has been neglected, with only a handful of methods tested due to their poor intelligibility. We approach the problem of interpretability in a novel way by proposing TSInsight, where we attach an auto-encoder to the classifier with a sparsity-inducing norm on its output and fine-tune it based on the gradients from the classifier and a reconstruction penalty. TSInsight learns to preserve features that are important for prediction by the classifier and suppresses those that are irrelevant, i.e., serves as a feature attribution method to boost the interpretability. In contrast to most other attribution frameworks, TSInsight is capable of generating both instance-based and model-based explanations. We evaluated TSInsight along with nine other commonly used attribution methods on eight different time series datasets to validate its efficacy. The evaluation results show that TSInsight naturally achieves output space contraction; therefore, it is an effective tool for the interpretability of deep time series models.

3.
BMC Med Inform Decis Mak ; 19(1): 136, 2019 07 17.
Artigo em Inglês | MEDLINE | ID: mdl-31315618

RESUMO

BACKGROUND: With the advancement of powerful image processing and machine learning techniques, Computer Aided Diagnosis has become ever more prevalent in all fields of medicine including ophthalmology. These methods continue to provide reliable and standardized large scale screening of various image modalities to assist clinicians in identifying diseases. Since optic disc is the most important part of retinal fundus image for glaucoma detection, this paper proposes a two-stage framework that first detects and localizes optic disc and then classifies it into healthy or glaucomatous. METHODS: The first stage is based on Regions with Convolutional Neural Network (RCNN) and is responsible for localizing and extracting optic disc from a retinal fundus image while the second stage uses Deep Convolutional Neural Network to classify the extracted disc into healthy or glaucomatous. Unfortunately, none of the publicly available retinal fundus image datasets provides any bounding box ground truth required for disc localization. Therefore, in addition to the proposed solution, we also developed a rule-based semi-automatic ground truth generation method that provides necessary annotations for training RCNN based model for automated disc localization. RESULTS: The proposed method is evaluated on seven publicly available datasets for disc localization and on ORIGA dataset, which is the largest publicly available dataset with healthy and glaucoma labels, for glaucoma classification. The results of automatic localization mark new state-of-the-art on six datasets with accuracy reaching 100% on four of them. For glaucoma classification we achieved Area Under the Receiver Operating Characteristic Curve equal to 0.874 which is 2.7% relative improvement over the state-of-the-art results previously obtained for classification on ORIGA dataset. CONCLUSION: Once trained on carefully annotated data, Deep Learning based methods for optic disc detection and localization are not only robust, accurate and fully automated but also eliminates the need for dataset-dependent heuristic algorithms. Our empirical evaluation of glaucoma classification on ORIGA reveals that reporting only Area Under the Curve, for datasets with class imbalance and without pre-defined train and test splits, does not portray true picture of the classifier's performance and calls for additional performance metrics to substantiate the results.


Assuntos
Aprendizado Profundo , Diagnóstico por Computador/métodos , Fundo de Olho , Glaucoma/diagnóstico por imagem , Interpretação de Imagem Assistida por Computador/métodos , Disco Óptico/diagnóstico por imagem , Humanos
4.
Sensors (Basel) ; 19(11)2019 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-31146357

RESUMO

The need for robust unsupervised anomaly detection in streaming data is increasing rapidly in the current era of smart devices, where enormous data are gathered from numerous sensors. These sensors record the internal state of a machine, the external environment, and the interaction of machines with other machines and humans. It is of prime importance to leverage this information in order to minimize downtime of machines, or even avoid downtime completely by constant monitoring. Since each device generates a different type of streaming data, it is normally the case that a specific kind of anomaly detection technique performs better than the others depending on the data type. For some types of data and use-cases, statistical anomaly detection techniques work better, whereas for others, deep learning-based techniques are preferred. In this paper, we present a novel anomaly detection technique, FuseAD, which takes advantage of both statistical and deep-learning-based approaches by fusing them together in a residual fashion. The obtained results show an increase in area under the curve (AUC) as compared to state-of-the-art anomaly detection methods when FuseAD is tested on a publicly available dataset (Yahoo Webscope benchmark). The obtained results advocate that this fusion-based technique can obtain the best of both worlds by combining their strengths and complementing their weaknesses. We also perform an ablation study to quantify the contribution of the individual components in FuseAD, i.e., the statistical ARIMA model as well as the deep-learning-based convolutional neural network (CNN) model.

5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 2377-2380, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29060376

RESUMO

This paper presents a wireless, low power and low cost two part wearable for real-time epileptic seizure detection. Using parameters of Electro-cardiograph (ECG), Electro-dermal Activity (EDA), body motion and breathing rate (BR), a novel multi-criteria-decision-system (MCDS) is proposed that reduces false alarms and true negatives. The combination of a chest and hand worn wearable continuously senses these parameters transmitting the data to a smart phone application via BLE 4.0 where long-short-term-memory (LSTM) based anomaly detection algorithms and logistic classifiers decide on the occurrence of the seizure in real time. A 96% precision and 90% recall is achieved through testing on synthetic data.


Assuntos
Dispositivos Eletrônicos Vestíveis , Algoritmos , Humanos , Monitorização Fisiológica , Convulsões , Smartphone
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