RESUMO
The differences in arterial blood pressure in the sample of population in the age of 60 and older of different ethnic groups in Yakutsk, as well as its connection with the other cardiovascular diseases risk factors have been analyzed. It was shown that the average values of systolic and diastolic blood pressure in subsample of the Yakuts appeared to be lower than in Caucasoid gerontic persons. The average values of systolic arterial blood pressure both in the Yakuts and in the Caucasoids were detected higher than normal values in all age-dependent subgroups. The average values of diastolic blood pressure in both ethnic groups were within the limits of high normal level. From 60 to 90 years and older the decrease in systolic and diastolic arterial blood pressure was detected; it was more marked in Caucasoid gerontic persons. The average values of pulse pressure in the Yakuts and in the Caucasoids appeared to be higher than the existing standard and didn't have any differences in ethnic groups. In both ethnical subsamples, pulse pressure values increase was observed in persons of 60-89 years old and its decrease after 90. Persons with overweight, obesity, central (abdominal) obesity, dyslypoproteidemias irrespective of belonging to ethnical group were characterized as having higher levels of arterial blood pressure. Statistically significant differences in the levels of arterial blood pressure in the Yakuts and in the Caucasoids depending on hyperglycemia, smoking, the presence of burdened anamnesis, educational level, marital status was not detected.
Assuntos
Pressão Arterial/fisiologia , Doenças Cardiovasculares/etnologia , Etnicidade , Idoso , Idoso de 80 Anos ou mais , Doenças Cardiovasculares/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Federação Russa/epidemiologiaRESUMO
X-irradiation with a dose of 8 Gy leads to a sharp decrease in membrane potential of cultured Chinese hamster cells followed by restoration thereof. Changes in the membrane potential are accompanied by a monotonous increase of mean values of input cell resistance. It is assumed that radiation elicits a decrease in the resistance of a plasma membrane and a concurrent increase in the resistance of intercellular gap contacts which lead to impairment of cell interaction.
Assuntos
Condutividade Elétrica , Potenciais da Membrana/efeitos da radiação , Animais , Células Cultivadas/efeitos da radiação , Cricetinae , Cricetulus , Fibroblastos/efeitos da radiaçãoAssuntos
Lipídeos de Membrana/metabolismo , Retina/fisiologia , Potenciais de Ação/efeitos dos fármacos , Animais , Antioxidantes/farmacologia , Anuros , Eletrorretinografia , Técnicas In Vitro , Potenciais da Membrana/efeitos dos fármacos , Microscopia Eletrônica , Peróxidos/metabolismo , Células Fotorreceptoras/fisiologia , Rana temporaria , Retina/metabolismo , Retina/ultraestruturaAssuntos
Células Fotorreceptoras/fisiologia , Animais , Ácido Aspártico/farmacologia , Cálcio/metabolismo , Permeabilidade da Membrana Celular , Estimulação Elétrica , Retroalimentação , Junções Intercelulares/ultraestrutura , Luz , Magnésio/farmacologia , Potenciais da Membrana , Microscopia Eletrônica , Células Fotorreceptoras/efeitos dos fármacos , Células Fotorreceptoras/ultraestrutura , Potássio/metabolismo , Sódio/metabolismo , Transmissão Sináptica , Tartarugas/fisiologia , Vertebrados/fisiologiaRESUMO
The amplitude and shape of the rod photoresponses were investigated at different intensity, duration, wavelength and diameter of the light spot. Intracellular recordings were performed from the green and red rod outer sigments. An increase in the light intensity produced an increase in the amplitude and a decrease in the time rise of the response. An intensive light flash suppressed for a time the rod sensitivity to test flashes. At light spots of large diameter (100--1500 mum) delayed depolarizing deflection was observed. The latter was conditioned by illumination of receptor surroundings and, apparently, was due to horizontal cells activity. The possible role of the depolarizing effect of the rod surroundings illumination is discussed.