RESUMO
The study with the two genetic markers--HLA antigens and the pattern of dermatoglyphics--provides strong evidence for the fact that there is a genetic predisposition to coronary heart disease. The dermatoglyphic pattern has been found to be a more reliable marker of predisposition to this disease than HLA antigens. The decisive rules derived from the study may be used in the assessment of a genetic risk for this cardiovascular abnormality.
Assuntos
Antígenos HLA/análise , Infarto do Miocárdio/genética , Dermatoglifia , Suscetibilidade a Doenças , Marcadores Genéticos , HumanosRESUMO
The dermatoglyphic studies showing the existence of genetic predisposition to the development of coronary heart disease were conducted. Methods based on the mathematical theory of pattern recognition were used for multifactorial analysis of the material. It was established that complex evaluation of 20 dermatoglyphic parameters could be reliable in predicting genetic risk factor in the development of this cardiovascular pathology.