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2.
BMJ ; 3632018.
Artigo em Inglês | BIGG - guias GRADE | ID: biblio-1015429

RESUMO

What is the best way to use oxygen therapy for patients with an acute medical illness? A systematic review published in the Lancet in April 2018 found that supplemental oxygen in inpatients with normal oxygen saturation increases mortality.1 Its authors concluded that oxygen should be administered conservatively, but they did not make specific recommendations on how to do it. An international expert panel used that review to inform this guideline. It aims to promptly and transparently translate potentially practice-changing evidence to usable recommendations for clinicians and patients.2 The panel used the GRADE framework and following standards for trustworthy guidelines.3


Assuntos
Humanos , Oxigênio/sangue , Oxigenoterapia/métodos , Oximetria/classificação , Acidente Vascular Cerebral/sangue , Acidente Vascular Cerebral/terapia , Oxigenoterapia , Doença Aguda/terapia , Infarto do Miocárdio
3.
HIV Med ; 14(5): 293-302, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-23171169

RESUMO

OBJECTIVES: Intimate partner violence (IPV) is a risk factor for HIV infection. Little is known, however, about the prevalence, clinical associations, and impact of IPV among patients living with HIV. METHODS: HIV-infected gay and bisexual men in Southern Alberta, Canada were screened for IPV between May 2009 and December 2011. The associations with IPV of sociodemographic factors, psychological factors, clinical status, and HIV-related and HIV-unrelated hospitalizations, data for which were obtained from a regional database, were evaluated using Poisson regression. RESULTS: Of 687 gay and bisexual patients, 22.4% had experienced one or several types of IPV. Patients disclosing IPV were more likely to be Aboriginal [adjusted prevalence ratio (APR) = 2.48; 95% confidence interval (CI) 1.18-5.20], to be younger (APR/year = 0.97; 95% CI 0.95-0.99), to be victims of childhood abuse (APR = 4.27; 95% CI 2.84-6.41), to be smokers (APR = 2.53; 95% CI 1.59-4.00), to have had depression prior to HIV diagnosis (APR = 1.87; 95% CI 1.10-3.16), to use ongoing psychiatric resources (APR = 3.53; 95% CI 2.05-6.10), to have recently participated in unprotected sex (APR = 2.29; 95% CI 1.10-4.77), and to have poor or fair vs. very good or excellent health-related quality of life (APR = 2.91; 95% CI 1.57-5.39). IPV was also associated with a higher rate of clinically relevant interruptions in care (APR = 1.95; 95% CI 1.23-3.08), a higher incidence of AIDS among patients presenting early to care (CD4 count ≥ 200 cells/µL; APR = 2.06; 95% CI 1.15-3.69), and an increased rate of HIV-related hospitalizations [relative risk (RR) = 1.55; 95% CI 0.99-2.33], especially after HIV diagnosis was established (RR = 2.46; 95% CI 1.51-3.99). CONCLUSIONS: The prevalence of IPV is high among HIV-infected gay and bisexual men and is associated with poor social, psychiatric, and medical outcomes. IPV is an under-recognized social determinant of health in this community that may be amenable to meaningful clinical interventions.


Assuntos
Bissexualidade , Depressão/epidemiologia , Soropositividade para HIV/epidemiologia , Homossexualidade Masculina , Adesão à Medicação/estatística & dados numéricos , Maus-Tratos Conjugais/estatística & dados numéricos , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Adulto , Alberta/epidemiologia , Indígena Americano ou Nativo do Alasca/etnologia , População Negra/etnologia , Contagem de Linfócito CD4 , Canadá , Depressão/etnologia , Depressão/psicologia , Soropositividade para HIV/etnologia , Soropositividade para HIV/psicologia , Hospitalização/estatística & dados numéricos , Humanos , Incidência , Masculino , Adesão à Medicação/etnologia , Adesão à Medicação/psicologia , Prevalência , Características de Residência , Fatores de Risco , Parceiros Sexuais/psicologia , Fatores Socioeconômicos , Maus-Tratos Conjugais/etnologia , Maus-Tratos Conjugais/prevenção & controle , Transtornos Relacionados ao Uso de Substâncias/etnologia , Transtornos Relacionados ao Uso de Substâncias/psicologia , Sexo sem Proteção , População Branca/etnologia
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