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1.
Ann Dermatol Venereol ; 139(1): 50-3, 2012 Jan.
Artigo em Francês | MEDLINE | ID: mdl-22225743

RESUMO

INTRODUCTION: Cutaneous syringotropic T-cell lymphoma is a rare form of lymphoma. We report a case involving a misleading cutaneous presentation on the sole of the foot. PATIENTS AND METHODS: A 55-year-old woman presented discrete coalescent papules on her left foot, having an anhidrotic appearance, for which a number of antifungal treatments had been given without success. The skin biopsy revealed CD4+ T lymphocytic dermal infiltrate, mainly near the sweat glands, with syringotropism. The diagnosis of syringotropic T-cell lymphoma was reinforced by the presence of dominant cutaneous T-lymphocyte clone in the skin biopsy. Staging tests were negative. Treatment was initiated with an extremely potent (class IV) dermal corticosteroid. DISCUSSION: Syringotropic T-cell lymphoma is an extremely rare form of cutaneous lymphoma similar in presentation to mycosis fungoides, characterised by the mainly perisudoral and syringotropic nature of the lymphocytic infiltrate. The value of this case report lies in the extremely mild nature of the misleading skin lesions, which could only be diagnosed through biopsy. Treatment for this condition is not as yet codified due to the extremely low number of cases reported in the literature.


Assuntos
Dermatomicoses/diagnóstico , Erros de Diagnóstico , Doenças do Pé/diagnóstico , Micose Fungoide/diagnóstico , Neoplasias Cutâneas/diagnóstico , Glândulas Sudoríparas/patologia , Carmustina/uso terapêutico , Clobetasol/uso terapêutico , Feminino , Doenças do Pé/induzido quimicamente , Doenças do Pé/tratamento farmacológico , Doenças do Pé/patologia , Humanos , Pessoa de Meia-Idade , Micose Fungoide/induzido quimicamente , Micose Fungoide/classificação , Micose Fungoide/tratamento farmacológico , Micose Fungoide/patologia , Pomadas/efeitos adversos , Neoplasias Cutâneas/induzido quimicamente , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/patologia
2.
Ann Dermatol Venereol ; 138(11): 736-8, 2011 Nov.
Artigo em Francês | MEDLINE | ID: mdl-22078033

RESUMO

BACKGROUND: Multiple cutaneous osteomas are a rare complication of chronic inflammatory acne that often goes unrecognized. We report a case concerning a 35-year-old woman. PATIENTS AND METHODS: A 35-year-old woman had been treated for acne since the age of 22 years, as part of which she received two courses of oral isotretinoin. We noted the secondary appearance of several microcysts on the face for which the excision was very difficult. Curiously, these small formations did not contain keratin but were very callous. Histological examination revealed foci of osseous metaplasia, probably of postinflammatory origin. Treatment consisted solely of excision of the lesions. DISCUSSION: Osteoma cutis comprises two distinct groups (primary and secondary). In our case, there were multiple cutaneous osteomas of the face resulting from chronic acne. The differential diagnosis was idiopathic miliary osteomatosis of the face, but this was ruled out by the young age of the patient, the improvement of the acneiform lesions under isotretinoin (confirming the initial diagnosis of acne) and the subsequent appearance of microcysts. Although there are as yet no codified treatments, excision appears to yield good results.


Assuntos
Acne Vulgar/complicações , Neoplasias Primárias Múltiplas/etiologia , Osteoma/etiologia , Neoplasias Cutâneas/etiologia , Acne Vulgar/tratamento farmacológico , Adulto , Antibacterianos/uso terapêutico , Fármacos Dermatológicos/uso terapêutico , Durapatita/análise , Feminino , Fenofibrato/uso terapêutico , Humanos , Hipertrigliceridemia/complicações , Hipertrigliceridemia/tratamento farmacológico , Hipolipemiantes/uso terapêutico , Isotretinoína/uso terapêutico , Minociclina/uso terapêutico , Neoplasias Primárias Múltiplas/química , Neoplasias Primárias Múltiplas/cirurgia , Osteoma/química , Osteoma/cirurgia , Neoplasias Cutâneas/química , Neoplasias Cutâneas/cirurgia
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