Lesion cutánea como primera manifestación de un adenocarcinoma gástrico / Skin lesion as first manifestation of gastric adenocarcinoma

Las metástasis cutáneas son poco frecuentes ysuelen aparecer en estadios finales de los cánceres.Sólo en un 0,8% de las ocasiones son la primeramanifestación de la neoplasia y se asocian a un pronósticoinfausto. Ante la existencia de cutánides debeconocerse que el tumor originario más frecuenteen mujeres es el de mama y en los hombres es el depulmón, en ambos sexos se siguen de los gastrointestinales.Presentamos el caso de un varón de 63años que consultó por una lesión nodular cutáneaque histológicamente mostró ser una metástasis deadenocarcinoma. El estudio de extensión confirmóla presencia de un adenocarcinoma gástrico metastático

Skin metastases are infrequent, generally of lateappearance and of very bad prognosis. They are thefirst symptom of cancer in 0.8% of cases. Theprognosis of patients with skin metastases is worstthan that for other localizations. The most frequentorigin of skin metastases are lung cancer in men andbreast cancer in women, followed by thegastrointestinal neoplasms. We present the case of a63 year old patient with a cutaneous lesion thathistopathology showed to be an adenocarcinoma.The workup study led to the diagnosis of metastaticgastric cancer

[Meningitis and brain abscess caused by Streptococcus intermedius in a patient infected with HIV-1]. / Meningitis y absceso cerebral por Streptococcus intermedius en un paciente con infección por VIH-1.

Streptococcus milleri group have been recognized as an important pathogens for abscess formation in various organs. Streptococci other than Streptococcus pneumoniae are a rare cause of bacterial meningitis in adults and can be associated with the presence of an undiagnosed brain abscess. Brain abscess is a focal collection within the brain parenchyma which can arise as a complication of a variety of infections. The most common etiologic organisms in clinical series have been microaerophilic streptococci and anaerobic bacteria. Although intracranial mass lesions that occur as a result of infection have commonly been reported in patients infected with the human immunodeficiency virus, brain abscess due to the common bacterial pathogens are rarely described in HIV infected patients and Toxoplasma gondii is the organism most frequently isolated from stereotactic brain biopsy in these patients. We report a patient with both HIV-1 infection and streptococcal meningitis secondary to brain abscess caused by S. intermedius.

Meningitis y absceso cerebral por Streptococcus intermedius en un paciente con infección por VIH-1 / Meningitis and brain abscess caused by streptpcoccus intermedius in a patient infected with HIV-1

Los estreptococos de grupo milleri se caracterizan por su tendencia a provocar infecciones piógenas invasoras en diferentes localizaciones. Las meningitis estreptocócicas no neumocócicas son poco frecuentes en pacientes adultos y pueden asociarse a la presencia de un absceso cerebral. Los abscesos cerebrales son colecciones localizadas dentro del parénquima cerebral que se originan como complicación de una infección, siendo los estreptococos microaerófilos y las bacterias anaerobiaslos microorganismos más frecuentemente aislados. Aunque no es inusual la presencia de colecciones intracraneales de etiología infecciosa en pacientes con infección por VIH-1, los abscesos cerebrales producidos por las bacterias piógenas habituales son muy infrecuentes y es T. gondiiel agente etiológico más frecuente. Aportamos un caso de meningitis y absceso cerebral por S. intermedius en un paciente con infección por VIH-1

Streptococcus milleri group have been recognized as an important pathogens for abscess formation in various organs. Streptococci other than Streptococcus pneumoniae are a rare cause of bacterial meningitis in adults and can be associated with the presence of an undiagnosed brain abscess. Brain abscess is a focal collection within the brain parenchyma wich can arise as a complication of a variety of infections. The most common etiologic organisms in clinical series have been microaerophilic streptococci and anaerobic bacterias. Although intracraneal mass lesions that occur as a result of infection have commonly been reported in patients infected with the human immunodeficiency virus, brain abscess due to the common bacterial pathogens are rarely described in HIV infected patients and Toxoplasma gondii is the organism most frecuently isolated from stereotactic brain biopsy in these patients. We report a patient with both HIV-1 infection and streptococcal meningitis secondary to brain abscess caused by S. intermedius