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Two unusual phorbol esters, namely 20-deoxyphorbol-3,4,12-triacetate-13-phenylacetate (1) and phorbol-3,4,12,13-tetraacetate-20-phenylacetate (2) plus ingol-3,8,12-triacetate-7-phenylacetate (3) were isolated from the latex of Euphorbia umbellata and identified by HRESIMS and 2D NMR. Compound 1 is herein described for the first time. Assignment of the phenylacetyl group at C-7 in compound 3 was suggested by the HMBC and NOESY spectra obtained in pyridine-d5. In addition to the latex and its distinct terpenoid fractions, the isolated compounds were tested as latent reversal agents against HIV-1-infected J-Lat cells, with reference to phorbol-12-myristate-13-acetate and ingenol-B. Compound 2 reverted 75-80% the viral latency on the GFP-positive cells, resulting EC50 3.70 µg/mL (SI 6.7), while 1 induced 34-40% reactivation at the same concentration range (4-20 µg/mL). The ingol derivative 3 was ineffective. Phorbol esters were confirmed as effective constituents in the latex since the fraction containing them was 2.4-fold more active than the lyophilised latex at the lowest concentration assayed.
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The aim of this study was to conduct a scoping and bibliometric review of swimming articles related to race analysis. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to identify relevant studies. Articles on race analysis in swimming published between 1984 and December 31, 2023 were retrieved from the Web of Science database. 366 records were screened and a total of 74 articles were retained for analysis. Until 2012, there were some time intervals with no or few publications. From 2012, there was a clear upward trend in publications and citations. This theme was led by the United States of America, Australia, and Spain. Australia and Spain maintain their status as the countries with the most publications. The analysis of author collaborations revealed two clusters with Spanish authors, and the remaining clusters are composed of Portuguese, Swiss, and Australian authors. With this bibliometric review, it has been possible to understand the evolution of the articles published on race analysis in swimming, the countries and the authors that have contributed most to this topic over the years. The prediction model shows that the number of articles and citations on this topic will continue to increase over the next 10 years (until 2034).
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Swimming performance is likely influenced by strength, but differences between butterfly, backstroke, breaststroke and front crawl, as well as between novice and expert swimmers, are unclear. We have examined the associations between sprint performances, upper and lower limb strength, and anthropometric characteristics in 14 (six males and eight females) non-elite and 16 (nine males and seven females) elite-level swimmers. After an anthropometric characterisation, participants performed four 25 m maximal swims (one per technique) with 10 min intervals, right and left shoulder flexion/extension isokinetic testing at 90 and 300º/s angular velocities and three countermovement jumps. Pearson correlation analysis showed that sprint times were moderate-largely negatively correlated with upper and lower limb strength and power (r ± 95%CI = 0.39 ± 0.26-0.77 ± 0.13, p < 0.05). Elite swimmers higher strength levels were associated with longer stroke length in butterfly and front crawl, and with higher stroke rate in backstroke and breaststroke (r ± 95%CI = 0.37 ± 0.32-0.68 ± 0.21; p < 0.05). Butterfly, backstroke and front crawl sprint times were moderate-largely negatively related with arm span (r ± 95%CI = 0.37 ± 0.26, 0.39 ± 0.25 and 0.69 ± 0.17, p < 0.05). The predictive model indicated that higher dry-land strength values distinguished elite from non-elite swimmers (r2 = 0.67-0.81; p < 0.001). This association was not observed per performance level and per sex, confirming that sprint swimming performance levels can be differentiated by dry-land strength testing.
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Natação , Extremidade Superior , Masculino , Feminino , Humanos , Ombro , Extremidade Inferior , AntropometriaRESUMO
The aim of this study was to analyze the agreement of the active drag coefficient measured through drag and propulsion methods. The sample was composed of 18 swimmers (nine boys: 15.9 ± 0.9 years; nine girls: 15.3 ± 1.2 years) recruited from a national swimming team. The velocity perturbation method was used as the drag measurement system and the Aquanex system as the propulsion system. For both sexes combined, the frontal surface area was 0.1128 ± 0.016 m2, swim velocity 1.54 ± 0.13 m.s-1, active drag 62.81 ± 11.37 N, propulsion 68.81 ± 12.41 N. The level of the active drag coefficient agreement was calculated based on the mean values comparison, simple linear regression, and Bland Altman plots. The mean data comparison revealed non-significant differences (p > 0.05) between methods to measure the active drag coefficient. Both the linear regression (R2 = 0.82, p < 0.001) and Bland Altman plots revealed a very high agreement. The active drag coefficient should be the main outcome used in the interpretation of the swimmers' hydrodynamic profile, because it is less sensitive to swimming velocity. Coaches and researchers should be aware that the active drag coefficient can also be calculated based on propulsion methods and not just based on drag methods. Thus, the swimming community can now use different equipment to measure the hydrodynamics of their swimmers.
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Distinct parts of Solanum torvum Swartz. (Solanaceae) are popularly used for a variety of therapeutic purposes. This study determined the phytochemical composition of a phenolic fraction of S. torvum leaf aqueous extract and investigated its antioxidant and liver-protective properties. A phenolic compound-enriched fraction, or phenolic fraction (STLAE-PF) of an infusion (STLAE) of S. torvum leaves, was tested in vitro (antagonism of H2O2 in cytotoxicity and DCF assays with HepG2/C3A cells), and in vivo for antioxidant activity and protective effects against acetaminophen (APAP)-induced liver injury in mice. Thirty-eight compounds (flavonoids, esters of hydroxycinnamic acid, and chlorogenic acid isomers) were tentatively identified (high-performance liquid chromatography coupled to high-resolution electrospray mass spectrometry) in the STLAE-PF fraction. In vitro assays in HepG2/C3A cells showed that STLAE-PF and some flavonoids contained in this phenolic fraction, at noncytotoxic levels, antagonized in a concentration-dependent manner the effects of a powerful oxidant agent (H2O2). In C57BL/6 mice, oral administration of STLAE (600 and 1,200 mg/kg bw) or STLAE-PF (300 mg/kg bw) prevented the rise in serum transaminases (ALT and AST), depletion of reduced glutathione (GSH) and elevation of thiobarbituric acid reactive species (TBARs) levels in the liver caused by APAP (600 mg/kg bw, i.p.). The hepatoprotective effects of STLAE-PF (300 mg/kg bw) against APAP-caused liver injury were comparable to those of N-acetyl-cysteine (NAC 300 or 600 mg/kg bw i.p.). These findings indicate that a phenolic fraction of S. torvum leaf extract (STLAE-PF) is a new phytotherapeutic agent potentially useful for preventing/treating liver injury caused by APAP overdosing.
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Doença Hepática Crônica Induzida por Substâncias e Drogas , Doença Hepática Induzida por Substâncias e Drogas , Solanum , Camundongos , Animais , Acetaminofen/toxicidade , Peróxido de Hidrogênio/toxicidade , Extratos Vegetais , Camundongos Endogâmicos C57BL , Antioxidantes/farmacologia , Antioxidantes/uso terapêutico , Fígado , Fenóis/farmacologia , Flavonoides/farmacologia , Flavonoides/análise , Doença Hepática Induzida por Substâncias e Drogas/etiologia , Doença Hepática Induzida por Substâncias e Drogas/prevenção & controle , Doença Hepática Induzida por Substâncias e Drogas/tratamento farmacológicoRESUMO
Compensatory training sessions have been highlighted as useful strategies to solve the differential weekly training load between the players' starting status. However, the influence of the players' starting status is still understudied in sub-elite youth football. Thus, the aim of this study was to compare the weekly training load on a standard microcycle in starters and non-starters of a sub-elite youth football academy. The weekly training load of 60 young sub-elite football players was monitored during a 6-week period using an 18 Hz global positioning system (GPS), 1 Hz telemetry heart rate, rating of perceived exertion (RPE), and total quality recovery (TQR). The total distance (TD) covered presented a significant difference between starters and non-starters with a moderate effect (t = -2.38, Δ = -428.03 m, p = 0.018, d = 0.26). Training volume was higher in non-starters than in starter players (TDStarters = 5105.53 ± 1684.22 vs. TDNon-starters = 5533.56 ± 1549.26 m). Significant interactive effects were found between a player's starting status, playing time, and session duration in overall training load variables for within (F = 140.46; η2 = 0.85; p < 0.001) and between-subjects (F = 11.63 to 160.70; η2 = 0.05 to 0.76; p < 0.001). The player's starting status seems to only influence the training volume in sub-elite youth football, unless one considers the covariance of the playing time and session duration. Consequently, coaches should prioritize complementary training to equalize training volume and emphasize similar practice opportunities for non-starters. Future studies should evaluate the gap between training and match load, measuring the impact of recovery and compensatory sessions.
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Futebol Americano , Futebol , Adolescente , Sistemas de Informação Geográfica , Frequência Cardíaca , Humanos , Futebol/fisiologiaRESUMO
The aims of this study were 1) to analyze the influence of chronological age, relative age, and biological maturation on accumulated training load and perceived exertion in young sub-elite football players and 2) to understand the interaction effects amongst age grouping, maturation status, and birth quartiles on accumulated training load and perceived exertion in this target population. A 6-week period (18 training sessions and 324 observation cases) concerning 60 young male sub-elite football players grouped into relative age (Q1 to Q4), age group (U15, U17, and U19), and maturation status (Pre-peak height velocity (PHV), Mid-PHV, and Post-PHV) was established. External training load data were collected using 18 Hz global positioning system technology (GPS), heart-rate measures by a 1 Hz short-range telemetry system, and perceived exertion with total quality recovery (TQR) and rating of perceived exertion (RPE). U17 players and U15 players were 2.35 (95% CI: 1.25-4.51) and 1.60 (95% CI: 0.19-4.33) times more likely to pertain to Q1 and Q3, respectively. A negative magnitude for odds ratio was found in all four quartile comparisons within maturation status (95% CI: 6.72-0.64), except for Mid-PHV on Q2 (95% CI: 0.19-4.33). Between- and within-subject analysis reported significant differences in all variables on age group comparison measures (F = 0.439 to 26.636, p = 0.000 to 0.019, η2 = 0.003-0.037), except for dynamic stress load (DSL). Between-subject analysis on maturity status comparison demonstrated significant differences for all training load measures (F = 6.593 to 14.424, p = 0.000 to 0.037, η2 = 0.020-0.092). Interaction effects were found for age group x maturity band x relative age (Λ Pillai's = 0.391, Λ Wilk's = 0.609, F = 11.385, p = 0.000, η2 = 0.391) and maturity band x relative age (Λ Pillai's = 0.252, Λ Wilk's = 0.769, F = 0.955, p = 0.004, η2 = 0.112). Current research has confirmed the effects of chronological age, relative age, and biological maturation on accumulated training load. Perceived exertion does not seem to show any differences concerning age group or maturity status. Evidence should be helpful for professionals to optimize the training process and young football players' performance.
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The aim of this study was to (1) analyze and compare the race performance and stability between the fastest and slowest male swimmers during the 50 m freestyle event, and (2) to understand the speed-time relationship in this race. The performances (start, clean swim, and finish) of 86 swimmers (divided into two tiers: best and poorest performances) who competed in the 50 m freestyle event in the 2019 long course LEN European Junior Championships were analyzed. The swimming speed presented a significant difference between the groups (tier #1 vs tier #2) in all sections of the race, in which the start (S0-15 m: p < 0.001, d = 1.64) and finish sections (S45-50: p < 0.001, d = 1.63) showed the greatest differences. Significant variances over the race sections were noted for both groups in all variables, in which the swimming speed was the variable with the highest variance (tier #1: p < 0.001, η2 = 0.72; tier #2: p < 0.001, η2 = 0.82). Both groups exhibited a similar normative stability, with the fastest swimmers tending to be the best in all sections. The fit analysis produced a cubic speed-time relationship. Notwithstanding, junior swimmers who raced the 50 m freestyle can be considered to have an all-out pacing. This information is of paramount importance for coaches and swimmers to understand the intra-lap race performance in this short event.
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Desempenho Atlético , Comportamento Competitivo , Natação , Humanos , MasculinoRESUMO
Introduction: In youth swimming, researchers are interested in understanding how anthropometry and parameters related to swimming technique (biomechanics, energetics, and efficiency) influence the performance. However, there is not any review in the literature that consolidates the body of knowledge of this topic. The objective of this study was to review systematically the current body of work on the influence of determinant factors related to swimming technique (biomechanics, energetics, and efficiency) and anthropometry in the young performance of swimmers. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to identify relevant studies. Results: After screening, 240 studies were analyzed and 59 related to swimming performance, and its determinant factors were retained for synthesis. Studies revealed a high-quality index by PEDro scale (mean score was 7.17 ± 1.40). Twenty-five studies were longitudinal designs and the remaining 34 cross-sectional designs. Most of the studies (N = 39, 66.1%) reported concurrently two or more determinant factors (anthropometrics, biomechanics, energetics, and efficiency). Conclusion: Youth swimming research relies on a multifactorial assessment. From the synthesis, it is possible to conclude that the performance of young swimmers is characterized by a multifactorial, holistic, and dynamic phenomenon. Better performance has always been related to better swimming technique and higher anthropometrics. This suggests that both anthropometrics (i.e., nature) and training (i.e., nurture) play key roles in the swimming performance of young swimmers.
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The purpose of this study was to analyze the acute effects of a standardized water training session on the shoulder rotators strength and balance in age group swimmers, in order to understand whether a muscle-strengthening workout immediately after the water training is appropriate. A repeated measures design was implemented with two measurements performed before and after a standardized swim session. 127 participants were assembled in male (n = 72; age: 16.28 ± 1.55 years, height: 174.15 ± 7.89 cm, weight: 63.97 ± 6.51 kg) and female (n = 55; age: 15.29 ± 1.28 years, height: 163.03 ± 7.19 cm, weight: 52.72 ± 5.48 kg) cohorts. The isometric torque of the shoulder internal (IR) and external (ER) rotators, as well as the ER/IR ratios, were assessed using a hand-held dynamometer. Paired sample t-tests and effect sizes (Cohen's d) were used (p ≤ 0.05). No significant differences were found on the shoulder rotators strength or balance in males after training. Females exhibited unchanged strength values after practice, but there was a considerable decrease in the shoulder rotators balance of the non-dominant limb (p < 0.01 d = 0.366). This indicates that a single practice seems not to affect the shoulders strength and balance of adolescent swimmers, but this can be a gender specific phenomenon. While muscle-strengthening workout after the water session may be appropriate for males, it can be questionable regarding females. Swimming coaches should regularly assess shoulder strength levels in order to individually identify swimmers who may or may not be able to practice muscle strengthening after the water training.
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Articulação do Ombro , Ombro , Adolescente , Feminino , Humanos , Masculino , Força Muscular , Amplitude de Movimento Articular , Natação , TorqueRESUMO
The aim of this study was to analyze the association between coaches' experience and their perceptions on the implementation of a long-term athletic development (LTAD) model created in 2016 by the Portuguese Swimming Federation. Eighty-six swimming coaches were assembled in groups according to their experience level: "novice" (n = 24), "intermediate" (n = 26), and "experienced" (n = 36), and they answered a questionnaire with the following items: (i) awareness of the existing model (ii) acceptance (iii) usefulness for practice, and (iv) implementation of this model by their peers. Regardless of experience, ~67% of the coaches were aware of the model. Among those, a large number showed acceptance (~95%) and confidence in its usefulness (~83%) for their daily practice. Most coaches (92%) showed concerns about the fact that their peers do not respect the model frameworks, declaring the search for their swimmers' immediate success (~58%) as the main cause for such behavior. The results also showed an association between experience and knowledge about the model's existence [χ 2 (2) = 10.223, p < 0.01, V = 0.345], and experienced coaches exhibited better knowledge than their intermediate [χ 2 (2) = 9.555, p < 0.01, V = 0.393] or novice [χ 2 (2) = 5.926, p = 0.02, V = 0.314] counterparts. While there was an association between the coaches' experience and knowledge about the LTAD model's existence, this situation does not seem to influence the way coaches accept and understand the usefulness of the model for their daily practice.
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(1) Background: Training load monitoring has become a relevant research-practice gap to control training and match demands in team sports. However, there are no systematic reviews about accumulated training and match load in football. (2) Methods: Following the preferred reporting item for systematic reviews and meta-analyses (PRISMA), a systematic search of relevant English-language articles was performed from earliest record to March 2020. The search included descriptors relevant to football, training load, and periodization. (3) Results: The literature search returned 7972 articles (WoS = 1204; Pub-Med = 869, SCOPUS = 5083, and SportDiscus = 816). After screening, 36 full-text articles met the inclusion criteria and were reviewed. Eleven of the included articles analyzed weekly training load distribution; fourteen, the weekly training load and match load distribution; and eleven were about internal and external load relationships during training. The reviewed articles were based on short-telemetry systems (n = 12), global positioning tracking systems (n = 25), local position measurement systems (n = 3), and multiple-camera systems (n = 3). External load measures were quantified with distance and covered distance in different speed zones (n = 27), acceleration and deceleration (n = 13) thresholds, accelerometer metrics (n = 11), metabolic power output (n = 4), and ratios/scores (n = 6). Additionally, the internal load measures were reported with perceived exertion (n = 16); heart-rate-based measures were reported in twelve studies (n = 12). (4) Conclusions: The weekly microcycle presented a high loading variation and a limited variation across a competitive season. The magnitude of loading variation seems to be influenced by the type of week, player's starting status, playing positions, age group, training mode and contextual variables. The literature has focused mainly on professional men; future research should be on the youth and female accumulated training/match load monitoring.
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Futebol Americano , Futebol , Aceleração , Adolescente , Feminino , Sistemas de Informação Geográfica , Humanos , Masculino , Estações do AnoRESUMO
Three known compounds, 20-deoxyphorbol-5ß-hydroxy-12-tiglate-13-isobutyrate (1), 20-deoxyphorbol-5ß-hydroxy-12-tiglate-13-phenylacetate (2), and 4-deoxy-4ß-phorbol-12-tiglate-13-phenylacetate (3), were reisolated from the latex of Euphorbia umbellata through a bioguided fractionation process to target HIV-1 latency reactivation. The in vitro bioassay using infected T-cell lymphoblasts (J-Lat 10.6), complemented with surface CD4 receptor downregulation assessment, led to isolation of the compounds as a highly active ternary mixture. Effective purification of the individual compounds was achieved by first subjecting a phorbol-enriched fraction (previously prepared from crude latex) to MPLC, followed by semipreparative HPLC and characterization by 1D and 2D NMR spectroscopy and (+)-HRESIMS. Compared with a positive control, the isolated compounds were effective in reactivating 68-75% of the virus latency in the range of 9.7-0.097 µM for compound 1, 8.85-0.088 µM for compound 2, and 9.1-0.091 µM for compound 3, with the latter maintaining steady effectiveness down to a 10-5 dilution. Accordingly, compound 3 may serve as a promising lead compound for the development of anti-HIV drugs based on latency reactivation therapy.
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Euphorbia/química , HIV-1/efeitos dos fármacos , Ésteres de Forbol/farmacologia , Latência Viral/efeitos dos fármacos , Brasil , Linhagem Celular , Humanos , Látex/química , Estrutura Molecular , Linfócitos T/virologiaRESUMO
Purpose: The aims of this study were to classify, identify and follow-up young swimmers' performance and its biomechanical determinants during two competitive seasons (in seven different moments of assessment-M), and analyze the individual variations of each swimmer. Method: Thirty young swimmers (14 boys: 12.70 ± 0.63 years-old; 16 girls: 11.72 ± 0.71 years-old) were recruited. A set of anthropometric, kinematic, efficiency, hydrodynamic and mechanical power variables were assessed. Results: The cluster solution (i.e., number of ideal clusters for this sample) resulted in three clusters, which were named as: cluster 1 ("talented"), cluster 2 ("proficient"), and cluster 3 ("non-proficient"). The performance improved between moments of assessment in all clusters (cluster 1-M1: 68.07 ± 6.62s vs M7: 61.46 ± 3.43s; cluster 2-M1: 73.14 ± 4.87s vs M7: 65.33 ± 2.97s; cluster 3-M1: 82.60 ± 4.18s vs M7: 70.09 ± 3.48s). Anthropometric features also increased between moments of assessment, and remaining biomechanical variables (kinematic, efficiency, hydrodynamic and mechanical power) also increased between M1 and M7, in all clusters. Cluster 1 increased their swimmer's membership between M1 and M7 (4 to 11), cluster 2 decreased (12 to 5), and cluster 3 maintained (14). Conclusion: It can be concluded that the cluster formation depends on different determinant factors during two competitive seasons, and young swimmers are prone to change from one cluster to another over this period of time.
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Desempenho Atlético/fisiologia , Comportamento Competitivo/fisiologia , Natação/fisiologia , Adolescente , Antropometria , Aptidão , Fenômenos Biomecânicos , Criança , Análise por Conglomerados , Interpretação Estatística de Dados , Feminino , Humanos , Hidrodinâmica , Estudos Longitudinais , MasculinoRESUMO
This study aimed to analyze the relationship between perceived aquatic competence (PAC) and real aquatic competence (RAC) in 6 to 10 year old children in skills identified as relevant for surviving an aquatic accident. The study sample consisted of 105 children (8.2 + 1.3 years old). Two age groups were examined separately [G1, 6 to 7 years (n = 53); G2, 8 to 10 years (n = 52)]. Children's aquatic competence was evaluated twice for skills linked to the risk of drowning: Firstly, using a common swimsuit (simple condition) and secondly wearing a t-shirt (complex condition). The PAC was assessed by questionnaire interview. Pearson correlation coefficients, pairwise, and independent t-test comparisons were performed with a significance level of 5%. Similar levels of PAC were found among both age groups for all measured skills, excepted for breath control during swimming (p < 0.05). However, PAC differs significantly (p < 0.001) from RAC (in simple and complex conditions) only in G1. Correlations between PAC and RAC were modest for all measured skills in both age-groups. Significant differences were found between RAC in simple and complex conditions in both groups (p < 0.01). Age contributes to a higher perceived aquatic competence in skills related to the risk of drowning.
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Afogamento , Natação , Desempenho Atlético , Criança , Humanos , Destreza Motora , Percepção , Inquéritos e QuestionáriosRESUMO
The main aim of this study was to compare the start, turn, and finish performance of 100 m and 200 m events in the four swimming strokes in elite swimmers of both sexes. The performances of all 128 finalists (64 males and 64 females) of the 100 m, and 200 m events at a major championship were analyzed. A set of variables related to the start, turn, and finish were assessed. In the start a significant and moderate race effect was verified in both sexes (100 m vs 200 m). It was highest in butterfly events (males: Δ = 9.81%, p = 0.046, η2 = 0.60; females: Δ = 7.96%, p < 0.001, η2 = 0.75). In the turn a significant and moderate-strong race effect was verified in all strokes in both sexes, the highest being in butterfly (males: Δ = 12.26%, p < 0.001, η2 = 0.93; females: Δ = 10.74%, p < 0.001, η2 = 0.92). The finish had a significant and moderate race effect in butterfly and in breaststroke (females). The underwater variables were found to be the main contributors to a faster start. Over the turn, key determinants were the surface variables. As for the finish, mixed results were observed. It can be suggested that the underwater profile was the main determinant in starting, whereas the surface profile was the main determinant in turning. Therefore, coaches are advised to focus on such race phases to enhance the total race time.
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Desempenho Atlético/fisiologia , Natação/fisiologia , Fenômenos Biomecânicos , Feminino , Humanos , Masculino , Destreza Motora/fisiologia , Tempo de Reação , Fatores de Tempo , Estudos de Tempo e MovimentoRESUMO
BACKGROUND: Stevia serrata Cav. (Asteraceae), widely found in Guatemala, is used to treat gastrointestinal problems. The aim of this study was to demonstrate the antinociceptive and anti-inflammatory effects of the essential oil (EO) and the mechanism of action. METHODS: EO was tested in chemical (capsaicin- and glutamate-induced licking response) or thermal (hot plate) models of nociception at 10, 30 or 100 mg/kg doses. The mechanism of action was evaluated using two receptor antagonists (naloxone, atropine) and an enzyme inhibitor (L-NAME). The anti-hyperalgesic effect was evaluated using carrageenan-induced nociception and evaluated in the hot plate. RESULTS: All three doses of EO reduced licking response induced by glutamate, and higher doses reduced capsaicin-induced licking. EO also increased area under the curve, similar to the morphine-treated group. The antinociceptive effect induced by EO was reversed by pretreatment of mice with naloxone (1 mg/kg, ip), atropine (1 mg/kg, ip) or L-NAME (3 mg/kg, ip). EO also demonstrated an anti-hyperalgesic effect. The 100 mg/kg dose increased the latency time, even at 1 h after oral administration and this effect has been maintained until the 96th hour, post-administration. CONCLUSIONS: Our data suggest that essential oil of S. serrata presents an antinociceptive effect mediated, at least in part, through activation of opioid, cholinergic and nitrergic pathways.
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BACKGROUND: Swimming relay events have the concern regarding a good start is shared between the incoming and outgoing swimmers. The aim of this study was to evaluate changes in exchange block time (EBT) for swimming relay events as a result of a four-week training program using the occlusion technique. METHODS: Twenty-eight national swimmers, 12 males (age: 17±1.83 years) and 16 females (age: 19.94±5.65 years) participated in this study. Subjects were required to undergo a training program on visual perception in relay swimming over the course of four weeks; they watched videos corresponding to the last movements of a swimmer during a 4×100m freestyle relay event. The videos were presented with temporal occlusion corresponding to predetermined approaching distances (7.5 m, 5.0 m, and 2.5 m). Swimmers were required to simulate a typical position for exiting the block and to estimate the time-to-contact of the incoming swimmer. The EBT was collected during a real 4×100-m freestyle competition before and after the application of the training program. RESULTS: Female swimmers showed a decreased in EBT, with an improvement of 1.42%, despite there not being a significant difference (P=0.68). The male swimmers had a higher improvement in EBT after the training, with a decrease of 13.34% (P=0.68). CONCLUSIONS: Visual perception practice using video occlusion techniques seems to have a positive effect. On EBT in swimming relay events, particularly in female swimmers.
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Desempenho Atlético/fisiologia , Desempenho Atlético/psicologia , Comportamento Competitivo/fisiologia , Condicionamento Físico Humano/métodos , Natação/fisiologia , Natação/psicologia , Percepção Visual/fisiologia , Adolescente , Feminino , Humanos , Masculino , Fatores Sexuais , Software , Fatores de Tempo , Adulto JovemRESUMO
This study aimed to identify potential predictors of 200 m front crawl performance at the winter season peak based on the anthropometric, physiological and biomechanical domains. Twelve expert male swimmers completed an incremental 7 × 200 m step test immediately after their most important winter competitions. Measurements were made of: (i) height, body mass and arm span as anthropometrical parameters; (ii) velocity at a 4 mmol·L-1 lactate concentration (V4), maximal oxygen uptake (VO2máx) and energy cost (C), as physiological parameters; (iii) stroke frequency (SF), stroke length (SL), stroke index (SI) and propelling efficiency (ηp) as biomechanical indicators; and (iv) 200 m front crawl race time in official long course competitions. Spearman correlation coefficients identified V4 as the single factor having significant relationship with performance. Simple regression analysis determined V4, SI and arm span as the most relevant variables of each group. Multiple linear regression models showed that physiological factors explained better (59%) the variation in performance at this stage of the season, followed by the biomechanical (14%) ones. Therefore, V4 can be one important aspect for training control and diagnosis for those who want to achieve success in the 200 m front crawl at the winter season peak.
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Antropometria , Desempenho Atlético , Natação , Atletas , Fenômenos Biomecânicos , Humanos , Masculino , Análise de Regressão , Estações do AnoRESUMO
Although performance and biomechanical evaluations are becoming more swimming-specific, dryland testing permits monitoring of a larger number of performance-related variables. However, as the degree of comparability of measurements conducted in-water and on land conditions is unclear, we aimed to assess the differences between force production in these two different conditions. Twelve elite swimmers performed a 30 s tethered swimming test and four isokinetic tests (shoulder and knee extension at 90 and 300°/s) to assess peak force, peak and average torque, and power symmetry index. We observed contralateral symmetry in all the tests performed, e.g., for 30 s tethered swimming and peak torque shoulder extension at 90°/s: 178 ± 50 vs. 183 ± 56 N (p = 0.38) and 95 ± 37 vs. 94 ± 35 N × m (p = 0.52). Moderate to very large direct relationships were evident between dryland testing and swimming force production (r = 0.62 to 0.96; p < 0.05). Swimmers maintained similar symmetry index values independently of the testing conditions (r = -0.06 to -0.41 and 0.04 to 0.44; p = 0.18-0.88). Asymmetries in water seems to be more related to technical constraints than muscular imbalances, but swimmers that displayed higher propulsive forces were the ones with greater force values on land. Thus, tethered swimming and isokinetic evaluations are useful for assessing muscular imbalances regarding propulsive force production and technical asymmetries.