[Chromoblastomycosis associated with leprosy: report of 2 cases]. / Associação de cromoblastomicose e hanseníase: relato de dois casos.

Thirty cases of chromoblastomycosis were diagnosed at Hospital dos Servidores do Estado do Maranhão, from November, 1988 to March, 1993. The authors report 2 (6.6%) cases, that presented an association with leprosy. The first patient developed both diseases together, showing palpable bilateral cubital nerves, perforanting ulcer of the right foot, infiltration and lesions in verrucoid plaques in left leg, with positive biopsy for dimorphic leprosy. The second case, a patient with history of lepromatous leprosy for 30 years without treatment, with vegetant lesions with a warty aspect in right elbow for 12 months, histopathologic and positive culture for chromoblastomycosis. The possible factors for development of this disease in these patients are discussed.

[The current status of diffuse cutaneous leishmaniasis (DCL) in the state of Maranhão. II. The epidemiological and clinico-evolutionary aspects]. / Estado atual da leishmaniose cutânea difusa (LCD) no Estado do Maranhão. II. Aspectos epidemiológicos, clínico-evolutivos.

The authors describe a retrospective and prospective study of 6 patients with diffuse cutaneous leishmaniasis observed in the state of Maranhão, since 1974. The patients come from different rural regions of the state and in all of them Leishmania (Leishmania) amazonensis was the cause five of the patients initiated their disease in the first decade of life. All the patients first had a solitary, nodular lesion, that after a variable period of time, disseminated and acquired other aspects. Sequentially the patients presented multiple nodular and ulcerative lesions, negative Leishmania skin tests and a refractory response to the therapeutic schedules used up to the present.

[Results of the use of a therapeutic protocol for Plasmodium vivax for 5 days in 3 municipalities of the São Luís Island, State of Maranhao, Brazil]. / Resultado do uso de um esquema terapêutico para Plasmodium vivax em cinco dias em três Muncípios da Ilha de São Luís, Estado do Maranhao, Brasil.

A uniform therapeutic schedule of Chloroquine 1500mg (three days) and Primaquine 75mg (adult 15mg x 5 days) was used in 1232 patients suffering from malaria due to Plasmodium vivax occurring in Island of São Luis Maranhão State in the period between January of 1984 and December 1985. Of the cases, 499 (40.5%) concluded treatment, and of these 448 were cured. Fifty one patients who relapsed responded to a second course of the treatment.