Nickel Oxy-Hydroxy/Multi-Wall Carbon Nanotubes Film Coupled with a 3D-Printed Device as a Nonenzymatic Glucose Sensor.

A rapid and simple method for the amperometric determination of glucose using a nanocomposite film of nickel oxyhydroxide and multi-walled carbon nanotube (MWCNTs) was evaluated. The NiHCF)/MWCNT electrode film was fabricated using the liquid-liquid interface method, and it was used as a precursor for the electrochemical synthesis of nickel oxy-hydroxy (Ni(OH)2/NiOOH/MWCNT). The interaction between nickel oxy-hydroxy and the MWCNTs provided a film that is stable over the electrode surface, with high surface area and excellent conductivity. The nanocomposite presented an excellent electrocatalytic activity for the oxidation of glucose in an alkaline medium. The sensitivity of the sensor was found to be 0.0561 µA µmol L-1, and a linear range from 0.1 to 150 µmol L-1 was obtained, with a good limit of detection (0.030 µmol L-1). The electrode exhibits a fast response (150 injections h-1) and a sensitive catalytic performance, which may be due to the high conductivity of MWCNT and the increased active surface area of the electrode. Additionally, a minimal difference in the slopes for ascending (0.0561 µA µmol L-1) and descending (0.0531 µA µmol L-1) was observed. Moreover, the sensor was applied to the detection of glucose in artificial plasma blood samples, achieving values of 89 to 98% of recovery.

A simple, fast, portable and selective system using carbon nanotubes films and a 3D-printed device for monitoring hydroxychloroquine in environmental samples.

In this work, an electrochemical method was developed for rapid and sensitive detection of hydroxychloroquine (HCQ), an ineffective candidate drug for COVID-19 treatment however widely consumed during the pandemic, in aqueous samples using a multi-walled carbon nanotubes (MWCNT) film produced through the interfacial method on the indium tin oxide electrode (ITO). According to Raman spectroscopy, X-ray diffraction, UV-vis spectroscopy, Energy-dispersive X-ray spectroscopy, scanning electron microscopy, and atomic force microscopy, the interfacial method produces homogeneous thin films of carbon nanotubes on the substrate surface, which keep connected to the surface forming a three-dimensional microporous structure. The electrochemical behavior and oxidation kinetics of HCQ were also investigated in the MWCNT film. The sensor showed a 7 times higher oxidation current for (69.88 µA) for HCQ than the ITO electrode (9.33 µA) due to the electrocatalytic properties MWCNTs. The ITO-modified electrode was assembled on a portable 3D-printed batch-injection cell for the amperometric detection of HCQ. The oxidation peak current of HCQ is linearly proportional to the concentrations of HCQ ranging from 1.0 to 100.0 µmol L-1, with a limit of detection of 0.27 µmol L-1. Water samples (river and tap water) were spiked with HCQ, without the need for dispendious pretreatment (except filtration), and analyzed by the portable system, revealing the detection of HCQ with the recovery of 92.0%-99.8%, which suggested the great potential for real environmental monitoring application.

Prussian blue-modified laser-induced graphene platforms for detection of hydrogen peroxide.

A laser-induced graphene (LIG) surface modified with Prussian blue (iron hexacyanoferrate) is demonstrated as a novel electrochemical sensing platform for the sensitive and selective detection of hydrogen peroxide. Electrochemical Prussian blue (PB) modification on porous graphene films engraved by infrared laser over flexible polyimide was accomplished. Scanning electron microscopy images combined with Raman spectra confirm the formation of porous graphene and homogenous electrodeposition of PB over this porous surface. Electrochemical impedance spectroscopy reveals a substantial decrease in the resistance to charge transfer values (from 395 to 31.4 Ω) after the PB insertion, which confirms the formation of a highly conductive PB-graphene composite. The synergistic properties of PB and porous graphene were investigated for the constant monitoring of hydrogen peroxide at 0.0 V vs. Ag|AgCl|KCl(sat.), under high-flow injections (166 µL s-1) confirming the high stability of the modified surface and fast response within a wide linear range (from 1 to 200 µmol L-1). Satisfactory detection limit (0.26 µmol L-1) and selectivity verified by the analysis of complex samples confirmed the excellent sensing performance of this platform. We highlight that the outstanding sensing characteristics of the developed sensor were superior in comparison with other PB-based or LIG-based electrochemical sensors reported for hydrogen peroxide detection.