Epidemiological analysis over two years of SARS-CoV-2 circulation in southern Brazil: old and novel predictors of COVID-19 outcome.

The overwhelming majority of SARS-CoV-2 epidemiological studies cover a narrow time period, making general knowledge about the COVID-19 pandemic difficult. To assess COVID-19-related host aspects in the overall pandemic, we analyzed COVID-19 cases during the first two years of SARS-CoV-2 circulation in southern Brazil. Herein, 390 patients admitted in 2020-2022 to a Brazilian public referral hospital were allocated into two groups according to the COVID-19 outcome: hospital discharge (n=237) or death (n=153). In the univariate analysis, several variables, including sociodemographic, clinical and laboratory aspects (primary data), were significantly different between the analyzed groups. In multivariate logistic regression, eight of these factors remained associated with the COVID-19 outcome. In particular, we report oxygen supplementation and the need for hemodialysis as predictors of hospital discharge and death from COVID-19, respectively. To the best of our knowledge, none of these findings have been previously reported in the Brazilian or world population. In conclusion, our results contribute to current knowledge by demonstrating that factors described at different times may remain associated with COVID-19 over the pandemic and by identifying novel predictors of COVID-19 outcome.

Tratamento endoscopico da litiase ureteral com extrator de Dormia. / Endoscopic treatment of urethral lithiasis with Dormia extractor

Os autores apresentam sua experiencia constante de 361 casos tratados com extrator de Dormia no periodo de outubro de 1976 a junho de 1979. Estudam a incidencia quanto ao sexo e idade; indicacao; localizacao e tamanho do calculo e analisam os resultados e complicacoes. Concluem pela validade da presente tecnica no tratamento da litiase do ureter inferior, pois obtiveram resultados satisfatorios e complicacoes quase sempre de pequena monta