[Ventricular arrhythmias in patients with ischemic heart disease: a possible role of the autonomous nervous system]. / Zheludochkovye narusheniia ritma u bol'nykh ishemicheskoi bolezn'iu serdtsa: vozmozhnaia rol' avtonomnoi nervnoi sistemy.

To reveal possible factors that initiate ventricular arrhythmias (VA) in patients with coronary heart disease (CHD), a total of 44 patients with documented coronary artery stenosis were examined. The patients underwent coronary ventriculography, bicycle ergometry, 24-hour Holter monitoring, and examination of the autonomic nervous system (ANS). In 24 patients (Group 1), myocardial ischemic episodes were accompanied by VA. The latter were absent in myocardial ischemia in 20 patients (Group 2). In the two groups, there were no statistically significant differences in parameters, such as severity of atherosclerotic lesion of coronary arteries, total ejection fraction, existence of regional asynergy, exercise tolerance, number of daily myocardial ischemic episodes, their duration, degree of ST segment displacement. Increased activity of the sympathetic ANS was detected in 20 (83.3%) patients from Group 1 and only in 3 (15%) from Group 2 (p < 0.05). It is suggested that enhanced functional activity of ANS may be a prerequisite for displaying arrhythmogenic mechanisms in myocardial ischemia.

[Combined use of cold (chloroethyl) and ergometry tests in the diagnosis of vasospastic angina]. / Kombinirovannoe primenenie kholodovoi (khlorétilovoi) i érgometrinovoi prob v diagnostike vazospasticheskoi stenokardii.

The study was undertaken to examine the informative value of cold (chloroethyl) and ergometrine tests in the diagnosis of vasospastic angina. A total of 36 patients with clinical and electrocardiographic signs of vasospastic angina were studied. They underwent coronary ventriculography, Holter monitoring, bicycle ergometry with continuously increasing or single submaximum exercise, pulmonary hyperventilation, cold, ergometrine, and chloroethyl tests. The examinations have shown that cold and ergometrine tests are of informative value in the diagnosis of vasospastic angina.

[Effectiveness of nitrosorbide, corinfar and obsidan in preventing ischemia caused by the dipyridamole test]. / Effektivnost' nitrosorbida, korinfara i obzidana v preduprezhdenii ishemii, vyzvannoi dipiridamolovoi proboi.

The efficacy of nitrosorbide, corinfar and obsidan in preventing myocardial ischemia, induced by exercise or intravenous dipyridamole, was evaluated in 20 coronary patients. Nitrosorbide was found to be the most effective, and obsidan, the least effective, drug in preventing the steal syndrome. It is suggested that the efficiency of anti-anginal drugs is based on their effect on coronary flow control as well as hemodynamic determinants of myocardial oxygen requirements. The dipyridamole test can be used for the assessment of the effects of antianginal agents.

[Comparative analysis of the information value of electrocardiographic loading tests in relation to the characteristics of atherosclerotic lesions of the coronary arteries]. / Sravnitel'nyi analiz informativnosti élektrokardiograficheskikh prob s nagruzkoi v zavisimosti ot osobennostei ateroskleroticheskogo porazheniia koronarnykh arterii.

Diagnostic possibilities of various exercise tests (bicycle ergometry, the dipyridamole test, atrial electrostimulation) were demonstrated, as was a relationship between their sensitivity and the number of stenosed coronary arteries, the extent and level of obstruction, collateral circulation specificity and myocardial function.