RESUMO
A new benzylisoquinoline alkaloid, argemexirine, together with two known protoberberine alkaloids, dl-tetrahydrocoptisine and dihydrocoptisine, have been isolated from the methanolic extract of the whole plant of Argemone mexicana L. The compounds were identified by spectral and chemical evidence. This is the first report of these alkaloids in this plant species.
Assuntos
Alcaloides/química , Argemone/química , Isoquinolinas/química , Alcaloides/isolamento & purificação , Berberina/análogos & derivados , Berberina/química , Isoquinolinas/isolamento & purificação , Espectroscopia de Ressonância Magnética , Metanol , Metilação , Extratos Vegetais/análise , Solventes , Espectrofotometria Infravermelho , Espectrofotometria UltravioletaRESUMO
This study was aimed to evaluate the immuno-modulator role of homeopathic remedies in Human Immunodeficiency Virus (HIV) infection. A randomised double blind clinical trial was conducted to compare the effect of homeopathic remedies with placebo, on CD4+ve T-lymphocytes in HIV infected individuals, conforming to Centres for Disease Control (CDC) stage II & III. 100 HIV+ve individual beteen 18-50y (71 percent males) were included in the study. 50 cases conformed... (AU)
Assuntos
Estudo Comparativo , Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Síndrome da Imunodeficiência Adquirida/terapia , Linfócitos T CD4-Positivos , ÍndiaRESUMO
A 6 month study comprising of a Double-blind Placebo-controlled trial of homoeopathic medicines in HIV/AIDS under 3 separate schemes (I) Asymptomatic HIV infection and (II) Persistent generalised lymphadenopathy (50 subjects each) was undertaken from June 1995 to February 1997. As soon as a subject had undergone 6 months of study, they were put on an indicated medicine. Unblinding... (AU)
Assuntos
Síndrome da Imunodeficiência Adquirida , Terapêutica Homeopática , ÍndiaRESUMO
To assess the role of homoeopathic medicines in the treatment of the asymptomatic phase of HIV infection, a pilot research study was undertaken by the Central Council for Research in Homoeopathy (India) starting in May 1989. 129 symptomatic HIV carriers (120 male and 9 female) were treated with homoeopathic medicines on the basis of the individuals' constitutional (both mental/emotional and physical) characteristics. The medicines were prescribed in potencies varying from 30CH to 10M and in varying dosage, depending on the age and constitution of the individual patients. 12 of the patients studied have reverted back to negative serology for HIV antibodies after treatment varying from 3 to 16 months (mean duration of treatment between entry and reversal of seroconversion for HIV antibodies 7.25 months). All patients who continue to remain symptom free are receiving follow-up treatment. Efforts are being made to evaluate their haematological and immunological status in detail