[Changes in the rat small intestine under conditions of disordered sympathetic and parasympathetic innervation]. / Izmeneniia tonkoi kishki krys v usloviiakh narusheniia simpaticheskoi i parasimpaticheskoi innervatsii.

Comparative study of vagotomy and desympathization results, performed by similar methods and in similar terms demonstrated that disturbance of sympathetic and parasympathetic innervation of small intestine is accompanied with acquiring of morphofunctional alterations, similar in reaction of local immune apparatus and in disorders of digestive, absorptive and excretory functions. Specific properties of vagotomy and desympathization effects mainly concern dynamics of destructive, dystrophic (atrophic), inflammatory and vascular changes, extent of expression of secretory function disturbances and of intensity of intestinal epithelium proliferation.

[Status of the mucous membrane of the jejunum of the rat after desympathization]. / Sostoianie slizistoi obolochki toshchei kishki krysy posle desimpatizatsii.

Desympathization of the rat jejunum has been performed by means of periarterial sympathectomy of the cranial mesenteric artery. In total preparations of the jejunum wall, by means of water-aldehyde method, catecholamines have been revealed for controlling desympathization effectiveness. Signs of reinnervation appear in 180 days after the operation. In paraffin sections, stained by general histological methods, morphometric analysis of the most important parameters of the mucous membrane is performed (height of the villi, depth of the crypts, villus/crypt index, height of the epithelium, amount of goblet cells and interepithelial lymphocytes) Height of the villi and villus/crypt index increase in 1, 3 and 14 days, while in 7 days after the operation depth of the crypts increases, and the index mentioned decreases. Height of epithelium in the villi decreases in 14, 30 and 90 days. In 3-30 days after the operation amount of interepithelial lymphocytes increases.

[Morphofunctional status of the small intestine after disruption of its extrinsic innervation]. / Morfofunktsional'noe sostoianie tonkoi kishki pri narushenii ee ékstraorgannoi innervatsii.

Within 6 months after decentralization of the rat and dog intestine, signs of reinnervation appear. Hypersecretion of the intestine juice, a decrease in the acetylcholine and noradrenaline contents, reduction of the invertase and alkaline phosphatase activity in the juice and homogenate of the small intestine occur during first weeks. The activating effect of the food on transmitter-enzymatic processes weakens whereas activity of the enteral nervous system is enhanced. The data obtained are significant for intestine transplantation research.