RESUMO
A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3'-formyl-5'-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-alpha-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.
Assuntos
Anagallis/química , Antimutagênicos/isolamento & purificação , Antioxidantes/isolamento & purificação , Flavonoides/isolamento & purificação , Mutagênicos/isolamento & purificação , Antioxidantes/química , Benzotiazóis/química , Compostos de Bifenilo/química , Escherichia coli/efeitos dos fármacos , Flavonoides/química , Flavonoides/farmacologia , Hidrazinas/química , Estrutura Molecular , Mutagênicos/química , Mutagênicos/farmacologia , Picratos , Ácidos Sulfônicos/químicaRESUMO
A new skeleton of an O-heteroside natural substance named zinolol, the first representative of a new class of aminated hydroxyhydroquinone, has been isolated from the whole plant Anagallis monelli. Its structure has been established by one and two dimensional NMR spectroscopic procedures. Antioxidant, mutagenic, antimutagenic activities were realised and positive results were recorded.