Clinically significant food preferences of patients with atrial fibrillation: a nosological and regional peculiarities.

AIM: The aim of the investigation was to study the peculiarities of food consumption in patients with atrial fibrillation, capable of influencing the anticoagulant therapy with warfarin, in comparison with healthy volunteers and taking into account geographical specifics. MATERIALS AND METHODS: In an open cohort study, 196 respondents (88 men, 108 women) evaluated food preferences using a questionnaire survey. The quantitative evaluation of adherence to lifestyle modification was studied by QAA-25. Statistical data processing was performed by parametric (Student's t-test) and nonparametric (Wald-Wolfowitz, Kolmogorov-Smirnov, Pearson) analysis methods. RESULTS: There were no statistically significant differences in food rations between the studied categories of respondents, both increasing [37.0±19.5 points versus 37.3±17.98 points; Wald-Wolfowitz (Z), p=0.16] and reducing the activity of warfarin [62.2±26.3 points versus 63.4±23.8 points; Wald-Wolfowitz (Z), p=0.95]. The absence of differences remained in the evaluation, taking into account regional characteristics of nutrition. The respondents were taking warfarin, there is no relationship between the level of commitment to the modification of lifestyle and diet modification. CONCLUSION: it is shown that medical recommendations aimed at correcting the eating behavior of respondents taking warfarin are not effective, which can be an independent risk factor for complications of both warfarin therapy and the underlying disease.

Quantitative assessment of adherence to treatment in patients with atrial fibrillation in real clinical practice.

AIM: To quantitatively evaluate features of adherence to treatment in patients with atrial fibrillation (AF) in Omsk region in conditions of real clinical practice. Materials and methods: in a prospective controlled study in 137 patients with AF 35-85 years quantitatively examined adherence to treatment and its structure. Statistical processing of data were performed using parametric (Student's t-test) and nonparametric (Wald-Wolfowitz, Kolmogorov-Smirnov, Pearson) analysis. MATERIALS AND METHODS: In a prospective controlled study in 137 patients with AF 35-85 years quantitatively examined adherence to treatment and its structure. Statistical processing of data were performed using parametric (Student's t-test) and nonparametric (Wald-Wolfowitz, Kolmogorov-Smirnov, Pearson) analysis. RESULTS: The most committed to treatment of AF patients older than 65 years. Regardless of age women are more committed to treatment than men. With increasing severity of AF symptoms in men, reduced adherence to treatment, in women is increasing commitment to the modification of lifestyle and drug therapy. In patients with paroxysmal AF adherence to drug therapy is higher than with a constant form. The increase in the number of comorbidities in men and women accompanied by a growing commitment to the modification of lifestyle and drug therapy, with a decrease in women adherence to medical support. If patients with AF the amount of medication increases, reduced adherence to medical support. CONCLUSION: Quantitative structural analysis of adherence to treatment in patients with AF identified previously do not consider the characteristics associated with gender, age, disease and drug therapy significantly influence treatment outcome.