Assuntos
Imagem de Difusão por Ressonância Magnética/métodos , Metotrexato/administração & dosagem , Metotrexato/efeitos adversos , Síndromes Neurotóxicas/diagnóstico , Síndromes Neurotóxicas/etiologia , Administração Oral , Feminino , Humanos , Imunossupressores/administração & dosagem , Imunossupressores/efeitos adversos , Pessoa de Meia-Idade , Síndromes Neurotóxicas/prevenção & controleRESUMO
The vestibulo-oculomotor response, i.e. the cervicoocular reflex (COR), to the stimulation of cervical proprioceptors by torso turns relative to the motionless head was studied in 15 human subjects under the conditions of labyrinthine and ocular differentiation. The COR coefficient of gain and phase shift were measured.
Assuntos
Movimentos da Cabeça/fisiologia , Propriocepção/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Adaptação Fisiológica , Adolescente , Adulto , Orelha Interna/fisiologia , Movimentos Oculares/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , RotaçãoRESUMO
Active cervicoocular reflex (ACOR) was studied in patients with unilateral vestibular dysfunction in decompensation and subcompensation. ACOR was evaluated by coefficient of reactivity, of involvement and phasic shift. ACOR can be used for staging vestibular dysfunction. Decompensation is accompanied by asymmetric ACOR, subcompensation--by symmetric one.
Assuntos
Orelha Interna/fisiopatologia , Neurônios Aferentes/fisiologia , Propriocepção/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Doenças Vestibulares/fisiopatologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Doenças Vestibulares/diagnósticoRESUMO
The study was made of passive cervicoocular reflex in patients with bilateral labyrinthine involvement. Passive cervicoocular reflex was assessed by three parameters: direction of the nystagmus, reactivity rate and phasic shift. It is proved that patients with bilateral labyrinthine lesions desplay intensive cervicoocular reflex serving the basic mechanism of vestibular dysfunction compensation in these patients.
Assuntos
Orelha Interna/fisiopatologia , Neurônios Aferentes/fisiologia , Propriocepção/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Doenças Vestibulares/fisiopatologia , Adulto , Feminino , Humanos , Índice de Gravidade de Doença , Doenças Vestibulares/diagnósticoRESUMO
Passive cervicoocular reflex (PCOR) was studied in patients with unilateral affection of the labyrinth at the stage of decompensation and subcompensation according to the following three criteria: nystagmic direction, reactivity coefficient and phasic deviation. In decompensation of unilateral vestibular dysfunction, PCOR presents intensively and asymmetrically while in subcompensation it becomes symmetric and less intensive. The PCOR is characterized as compensatory in unilateral lesion of peripheral vestibular system.
Assuntos
Vértebras Cervicais/fisiologia , Doenças do Labirinto/fisiopatologia , Neurônios Aferentes/fisiologia , Propriocepção/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Vestíbulo do Labirinto/fisiopatologia , Adulto , Idoso , Feminino , Humanos , Doenças do Labirinto/diagnóstico , Masculino , Mecanorreceptores/fisiologia , Pessoa de Meia-Idade , Testes de Função VestibularRESUMO
The vestibular-cervical-ocular reflex (VCOR) results from interaction of the labyrinthine and cervical proprioceptive afferent flows. VCOR study was performed in 20 healthy test subjects. Analyzed were the coefficient of reactivity, VCOR phase shift, coefficient of COR involvement, and the coefficient of VOR-VCOR asymmetry. Functional dependence of cervical proprioceptive and vestibular afferentation in the healthy test subjects was demonstrated.
