[Possible mechanisms of the emergence of chromosome rearrangements. VI. Mitotic delay as a protective mechanism. Origin of spontaneous chromosome breaks]. / Vozmozhnye mekhanizmy vozniknoveniia perestroek khromosom. VI. Zaderzhka mitoza kak protektornyi mekhanizm. Proiskhozhdenie spontannykh razryvov khromosom.

It was proved by the investigation of the bone marrow cells and the culture of embryonic fibroblasts of mice, that experimental induction of chromosome breaks having such a distinctive feature as disposition of acentrics outside the equatorial plate at metaphase, results in reduction of the mitotic index and the radiation induced structural mutations frequency. Such disposition of acentrics--outside the equatorial plate--is typical for spontaneous chromosome breaks. It was suggested, that the process resulting in spontaneous chromosome breaks is a component of the protective mechanism, which is put into effect through the mitotic delay.