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Interact Cardiovasc Thorac Surg ; 27(6): 881-883, 2018 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-29878119

RESUMO

Different types of oxidized cellulose have been used for haemorrhage control in thoracic surgery, abdominal surgery and neurosurgery. Oxidized resorbable cellulose (Gelita-cel) is a new haemostatic agent. Once saturated with blood, it swells and makes a gelatinous mass that formats as a fibrin clot. We have performed a prospective observational cohort study of patients operated for lung cancer or suspected lung cancer using Gelita-cel as a haemostatic agent. Between October 2010 and April 2012, 477 patients were operated in our department for lung cancer. Gelita-cel was used in 200 patients due to minor intraoperative haemorrhage after lymph node resection from Stations 2 to 11. During follow-up for lung cancer, computed tomography, which was performed 4-60 months after the primary operation, showed enlarged lymph nodes in the mediastinum in 16 patients. Endoscopic bronchial ultrasonographic biopsies of the lymph nodes showed foreign body material and granulomatous inflammation, and no sign of lung cancer recurrence. Gelita-cel has a high risk of causing granuloma and should not be used as a haemostatic agent in thoracic surgery.


Assuntos
Perda Sanguínea Cirúrgica/prevenção & controle , Carcinoma Pulmonar de Células não Pequenas/cirurgia , Celulose Oxidada/efeitos adversos , Reação a Corpo Estranho/induzido quimicamente , Neoplasias Pulmonares/cirurgia , Idoso , Idoso de 80 Anos ou mais , Biópsia , Broncoscopia , Carcinoma Pulmonar de Células não Pequenas/diagnóstico , Feminino , Seguimentos , Reação a Corpo Estranho/diagnóstico , Hemostáticos/efeitos adversos , Humanos , Neoplasias Pulmonares/diagnóstico , Masculino , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Estudos Prospectivos
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