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1.
Arkh Patol ; 84(2): 29-35, 2022.
Artigo em Russo | MEDLINE | ID: mdl-35417946

RESUMO

The article describes the clinical, radiological and pathological features of epithelioid hemangioendothelioma (EHE) in 27 adult patients, mainly female. In all cases, with the exception of one, there was a benign course of the disease over many years with a tendency to stabilize growth, the morphological sign of which was the development of widespread sclerotic changes. With the help of immunohistochemical method, the endothelial nature of EHE cells and its relatively low proliferative potential were confirmed. Clinical and morphological features of EHE raise the question of the essence of proliferation of endothelial cells with the formation of tumor-like nodes. There is every reason to consider EHE as a pseudotumor of the type of nodose hyperplasia in the nosological group of dyshormonal hyperplasia, similar to benign leiomyoma of the uterus with lung damage, as we have previously proposed.


Assuntos
Neoplasias Ósseas , Neoplasias da Mama , Hemangioendotelioma Epitelioide , Neoplasias Pulmonares , Neoplasias Cutâneas , Adulto , Neoplasias Ósseas/patologia , Neoplasias da Mama/patologia , Criança , Células Endoteliais/patologia , Feminino , Hemangioendotelioma Epitelioide/diagnóstico por imagem , Humanos , Hiperplasia/patologia , Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/patologia , Neoplasias Cutâneas/patologia
2.
Arkh Patol ; 80(1): 52-57, 2018.
Artigo em Russo | MEDLINE | ID: mdl-29460895

RESUMO

The paper presents the data available in the literature on the pathogenesis, clinical and morphological, histological and immunohistochemical features of pulmonary sclerosing pneumocytoma (SP). The paper gives the detailed histological and immunohistochemical characteristics of 6 SP cases. The need for the differential diagnosis of SP is determined by the features and complexity of their histo- and morphogenesis within a single tumor and a complex diagnostic study.


Assuntos
Hemangioma Esclerosante Pulmonar , Diagnóstico Diferencial , Humanos , Morfogênese , Hemangioma Esclerosante Pulmonar/diagnóstico , Hemangioma Esclerosante Pulmonar/patologia
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