1.
Rev Endocr Metab Disord
; 17(3): 247-258, 2016 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27761789
RESUMO
The skin is an important extra-gonadal steroidogenic organ, capable of metabolizing various hormones from their precursors, as well as of synthesizing de novo a broad palette of sex steroids and glucocorticoids from cholesterol. In this manuscript, we review the major steroidogenic properties of human skin and we suggest steroidogenesis' impairment as a cardinal factor for various pathological conditions such as acne, rosacea, atopic dermatitis, and androgenic alopecia.