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1.
Sensors (Basel) ; 22(13)2022 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-35808451

RESUMO

Health monitoring and related technologies are a rapidly growing area of research. To date, the electrocardiogram (ECG) remains a popular measurement tool in the evaluation and diagnosis of heart disease. The number of solutions involving ECG signal monitoring systems is growing exponentially in the literature. In this article, underestimated Orthogonal Matching Pursuit (OMP) algorithms are used, demonstrating the significant effect of concise representation parameters on improving the performance of the classification process. Cardiovascular disease classification models based on classical Machine Learning classifiers were defined and investigated. The study was undertaken on the recently published PTB-XL database, whose ECG signals were previously subjected to detailed analysis. The classification was realized for class 2, class 5, and class 15 cardiac diseases. A new method of detecting R-waves and, based on them, determining the location of QRS complexes was presented. Novel aggregation methods of ECG signal fragments containing QRS segments, necessary for tests for classical classifiers, were developed. As a result, it was proved that ECG signal subjected to algorithms of R wave detection, QRS complexes extraction, and resampling performs very well in classification using Decision Trees. The reason can be found in structuring the signal due to the actions mentioned above. The implementation of classification issues achieved the highest Accuracy of 90.4% in recognition of 2 classes, as compared to less than 78% for 5 classes and 71% for 15 classes.


Assuntos
Eletrocardiografia , Processamento de Sinais Assistido por Computador , Algoritmos , Arritmias Cardíacas/diagnóstico , Eletrocardiografia/métodos , Humanos , Aprendizado de Máquina
2.
Sensors (Basel) ; 22(3)2022 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-35161650

RESUMO

The electrocardiogram (ECG) is considered a fundamental of cardiology. The ECG consists of P, QRS, and T waves. Information provided from the signal based on the intervals and amplitudes of these waves is associated with various heart diseases. The first step in isolating the features of an ECG begins with the accurate detection of the R-peaks in the QRS complex. The database was based on the PTB-XL database, and the signals from Lead I-XII were analyzed. This research focuses on determining the Few-Shot Learning (FSL) applicability for ECG signal proximity-based classification. The study was conducted by training Deep Convolutional Neural Networks to recognize 2, 5, and 20 different heart disease classes. The results of the FSL network were compared with the evaluation score of the neural network performing softmax-based classification. The neural network proposed for this task interprets a set of QRS complexes extracted from ECG signals. The FSL network proved to have higher accuracy in classifying healthy/sick patients ranging from 93.2% to 89.2% than the softmax-based classification network, which achieved 90.5-89.2% accuracy. The proposed network also achieved better results in classifying five different disease classes than softmax-based counterparts with an accuracy of 80.2-77.9% as opposed to 77.1% to 75.1%. In addition, the method of R-peaks labeling and QRS complexes extraction has been implemented. This procedure converts a 12-lead signal into a set of R waves by using the detection algorithms and the k-mean algorithm.


Assuntos
Eletrocardiografia , Processamento de Sinais Assistido por Computador , Algoritmos , Arritmias Cardíacas , Humanos , Redes Neurais de Computação
3.
Sensors (Basel) ; 21(23)2021 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-34884029

RESUMO

Acute lymphoblastic leukemia is the most common cancer in children, and its diagnosis mainly includes microscopic blood tests of the bone marrow. Therefore, there is a need for a correct classification of white blood cells. The approach developed in this article is based on an optimized and small IoT-friendly neural network architecture. The application of learning transfer in hybrid artificial intelligence systems is offered. The hybrid system consisted of a MobileNet v2 encoder pre-trained on the ImageNet dataset and machine learning algorithms performing the role of the head. These were the XGBoost, Random Forest, and Decision Tree algorithms. In this work, the average accuracy was over 90%, reaching 97.4%. This work proves that using hybrid artificial intelligence systems for tasks with a low computational complexity of the processing units demonstrates a high classification accuracy. The methods used in this study, confirmed by the promising results, can be an effective tool in diagnosing other blood diseases, facilitating the work of a network of medical institutions to carry out the correct treatment schedule.


Assuntos
Inteligência Artificial , Leucemia-Linfoma Linfoblástico de Células Precursoras , Algoritmos , Humanos , Aprendizado de Máquina , Redes Neurais de Computação , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico
4.
Sensors (Basel) ; 21(24)2021 Dec 07.
Artigo em Inglês | MEDLINE | ID: mdl-34960267

RESUMO

Deep Neural Networks (DNNs) are state-of-the-art machine learning algorithms, the application of which in electrocardiographic signals is gaining importance. So far, limited studies or optimizations using DNN can be found using ECG databases. To explore and achieve effective ECG recognition, this paper presents a convolutional neural network to perform the encoding of a single QRS complex with the addition of entropy-based features. This study aims to determine what combination of signal information provides the best result for classification purposes. The analyzed information included the raw ECG signal, entropy-based features computed from raw ECG signals, extracted QRS complexes, and entropy-based features computed from extracted QRS complexes. The tests were based on the classification of 2, 5, and 20 classes of heart diseases. The research was carried out on the data contained in a PTB-XL database. An innovative method of extracting QRS complexes based on the aggregation of results from established algorithms for multi-lead signals using the k-mean method, at the same time, was presented. The obtained results prove that adding entropy-based features and extracted QRS complexes to the raw signal is beneficial. Raw signals with entropy-based features but without extracted QRS complexes performed much worse.


Assuntos
Aprendizado Profundo , Processamento de Sinais Assistido por Computador , Algoritmos , Eletrocardiografia , Redes Neurais de Computação
5.
Entropy (Basel) ; 23(9)2021 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-34573746

RESUMO

The analysis and processing of ECG signals are a key approach in the diagnosis of cardiovascular diseases. The main field of work in this area is classification, which is increasingly supported by machine learning-based algorithms. In this work, a deep neural network was developed for the automatic classification of primary ECG signals. The research was carried out on the data contained in a PTB-XL database. Three neural network architectures were proposed: the first based on the convolutional network, the second on SincNet, and the third on the convolutional network, but with additional entropy-based features. The dataset was divided into training, validation, and test sets in proportions of 70%, 15%, and 15%, respectively. The studies were conducted for 2, 5, and 20 classes of disease entities. The convolutional network with entropy features obtained the best classification result. The convolutional network without entropy-based features obtained a slightly less successful result, but had the highest computational efficiency, due to the significantly lower number of neurons.

6.
Entropy (Basel) ; 22(6)2020 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-33286369

RESUMO

Due to their growing number and increasing autonomy, drones and drone swarms are equipped with sophisticated algorithms that help them achieve mission objectives. Such algorithms vary in their quality such that their comparison requires a metric that would allow for their correct assessment. The novelty of this paper lies in analysing, defining and applying the construct of cross-entropy, known from thermodynamics and information theory, to swarms. It can be used as a synthetic measure of the robustness of algorithms that can control swarms in the case of obstacles and unforeseen problems. Based on this, robustness may be an important aspect of the overall quality. This paper presents the necessary formalisation and applies it to a few examples, based on generalised unexpected behaviour and the results of collision avoidance algorithms used to react to obstacles.

7.
Molecules ; 22(9)2017 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-28869569

RESUMO

Tribological surgical adjuvants constitute a therapeutic discipline made possible by surgical advances in the treatment of damaged articular cartilage beyond palliative care. The purpose of this study is to analyze interactions between hyaluronic acid and phospholipid molecules, and the formation of geometric forms, that play a role in the facilitated lubrication of synovial joint organ systems. The analysis includes an evaluation of the pathologic state to detail conditions that may be encountered by adjuvants during surgical convalescence. The synovial fluid changes in pH, hyaluronic acid polydispersity, and phospholipid concentration associated with osteoarthritis are presented as features that influence the lubricating properties of adjuvant candidates. Molecular dynamic simulation studies are presented, and the Rouse model is deployed, to rationalize low molecular weight hyaluronic acid behavior in an osteoarthritic environment of increased pH and phospholipid concentration. The results indicate that the hyaluronic acid radius of gyration time evolution is both pH- and phospholipid concentration-dependent. Specifically, dipalmitoylphosphatidylcholine induces hydrophobic interactions in the system, causing low molecular weight hyaluronic acid to shrink and at high concentration be absorbed into phospholipid vesicles. Low molecular weight hyaluronic acid appears to be insufficient for use as a tribological surgical adjuvant because an increased pH and phospholipid concentration induces decreased crosslinking that prevents the formation of supramolecular lubricating forms. Dipalmitoylphosphatidylcholine remains an adjuvant candidate for certain clinical situations. The need to reconcile osteoarthritic phenotypes is a prerequisite that should serve as a framework for future adjuvant design and subsequent tribological testing.


Assuntos
1,2-Dipalmitoilfosfatidilcolina/química , Quimioterapia Adjuvante/métodos , Ácido Hialurônico/química , Simulação de Dinâmica Molecular , Osteoartrite/tratamento farmacológico , 1,2-Dipalmitoilfosfatidilcolina/farmacologia , Cartilagem Articular/efeitos dos fármacos , Cartilagem Articular/metabolismo , Humanos , Ácido Hialurônico/farmacologia , Concentração de Íons de Hidrogênio , Interações Hidrofóbicas e Hidrofílicas , Lubrificação , Estrutura Molecular , Peso Molecular , Osteoartrite/metabolismo , Relação Estrutura-Atividade , Líquido Sinovial/metabolismo
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