EPIDEMIOLOGICAL INDICATORS OF DENTAL MORBIDITY OF CHILDREN AS AN INDICATOR OF ADVERSE ENVIRONMENTAL INFLUENCE.

OBJECTIVE: The aim: Is to study the ecological and hygienic situation in the living area of 6-year-old children in terms of drinking water (micro- and macroelements), to identify its relationship with the state of mineral metabolism in children's mouths, prevalence and intensity of temporary and permanent caries. PATIENTS AND METHODS: Materials and methods:Clinical and laboratory studies were to study the objective condition of the teeth -intensity of dental caries according to the recommendations of the WHO and the method of T.F. Vinogradova. The hygienic condition of the oral cavity was determined by the indices Silness-Loe, Stallard. RESULTS: Results: The results of our studies have shown that the proposed therapeutic and prophylactic complex, which includes drugs of endogenous (Vitafluor) and exogenous use (osteovitis, deep fluoridation, toothpastes "Splat junior" and "Lacalut fluor"), improves the hygienic state of the oral cavity, increases mineralizing the potential of the oral fluid and, as a result, helps to reduce the intensity of dental caries in children. CONCLUSION: Conclusions: The data obtained indicated a high caries prophylactic efficacy of the proposed therapeutic and prophylactic complex for 6-year-old children living in the zone of hypophtorosis.

EXPERIMENTAL MODEL OF AN INTEGRATED APPROACH TO THE TRAINING OF LEGAL AND HEALTH CARE PROFESSIONALS ON ISSUES OF INFECTION WITH ESPECIALLY DANGEROUS INFECTIOUS DISEASES.

OBJECTIVE: The aim: Developing integration training (educational) programs for medical and legal students, interns, masters, doctors. PATIENTS AND METHODS: Material and methods: When performing the work, on a set of search and analytical methods: analytical, bibliographic, systemic, informational, statistical; interdisciplinary interactive teaching methods for students of Sumy State University. RESULTS: Results: The results of the integrated training course are the formation of a new style of interdisciplinary relations between participants of the educational process and practical medicine and jurisprudence; new educational environment; classes with multi - and transdisciplinary experts-consultants; development of personal attitudes, future professional contacts, and practical skills. CONCLUSION: Conclusions: The introduction of new teaching methods using an interdisciplinary integrated approach increases the level of education quality (35.8% higher than the initial result) and conduct applied research in the field of public health, jurisprudence.

Indicators of left ventricle hypertrophy in patients with arterial hypertension combined with obesity and their interconnection with polymorphism of lys198asn genе of endothelin-1.

OBJECTIVE: The aim of the study was to find dependence of left ventricular hypertrophy indexes to polymorphism of Les198Asn gene endothelin-1 and BMI. PATIENTS AND METHODS: Materials and methods: We took research in 160 patients with arterial hypertension, using ECG and polymerase chain reaction (PCR). Groups were divided additionally according to BMI (body mass index). RESULTS: Results: It was found, that patients with obesity had their Left ventricular mass and hypertrophy left ventricular indexes higher, than in patients with normal and increased body weight. Carriers of Asn198Asn and Lys198Asn genotypes Left ventricular mass and hypertrophy left ventricular indexes are higher than in carriers of Lys198Lys genotype. CONCLUSION: Conclusions: It was determined that in patients-carriers of Asn198Asn genotype, Left ventricular mass (LVMI) and hypertrophy left ventricular indexes (LVMMI) were higher compared to patients-carriers of Lys198Lys and Lys198Asn type, both in men and women. The dependence of LVMI and LVMMI are shown to be higher in patients with obesity than in people with normal and increased body mass.

The main leitmotifs of chinese medicine in the context of the development of modern science.

OBJECTIVE: The aim: To demonstrate the limitations of pharmacological (chemical) therapy and the atomistic paradigm of science (in particular medicine) on the methodological basis of modern interdisciplinary directions (the theory of dissipative structures, chaos, autopoiesis), quantum mechanics, as well as the basic patterns of oriental medicine. PATIENTS AND METHODS: Materials and methods: The principles used in the article include self-organization, emergence, quantum mechanics (the Heisenberg uncertainty principle), the principle of consistency; principles of using coherent millimeter waves of low power, etc. Theoretical methods of analysis and synthesis, idealization, abstraction, induction and deduction are also used. CONCLUSION: Сonclusions: The concept of "integrable system" is equivalent to the concept of "integral quantum-mechanical system"; Integral quantum-mechanical systems (nuclei, atoms, molecules, living objects) in the ground state are described by periodic wave functions of the type exp (jwt); The traditional paradigm, for the most part, eliminates the qualitative difference between living and dead matter; Any living system functioning as a whole is simultaneously a macroscopic quantum-mechanical object and a millimeter-wave laser.