[Application of hemopoietic cells of embryonal human liver in treatment of pancreatic head cancer complicated by obturating jaundice]. / Primenenie gemopoéticheskikh kletok émbrional'noi pecheni cheloveka pri lechenii raka golovki podzheludochnoi obturatsionnoi zheltukhoi.

In 30 patients with pancreatic head cancer after surgical treatment of biliary ducts obstructions using biliodigestive shunting method the suspensions, containing stem cells of embryonal liver, were transplanted. The hematological and immunological indexes improvement was noted. After transplantation performance several courses of chemotherapy were conducted, promoting elongation of average life span by 50%.

[The characteristics of different types of mRNA expressed in the human brain]. / Kharakteristika razlichnykh tipov mRNK, ékspressiruiushchikhsia v golovnom mozge cheloveka.

Considerable decrease of expression of some "brain-specific" genes obtained in previous experiments was detected by means of differential hybridization of gridded human fetal brain cDNA library with total cDNA probes, synthetized on mRNAs isolated from the normal brain cells and several tumor cells. In contrast, for few genes expressed on low level in human fetal brain the evident increase of expression level in human brain tumour cells was found. The nucleotide sequences of some of these genes and previously isolated genes which have different specificity of expression were determined.

[An analysis of human genome expression by using libraries of the cDNA from different organs]. / Analiz ékspressii genoma cheloveka pri pomoshchi bibliotek kDNK razlichnykh organov.

The major liver and brain transcripts having different specificity of expression were isolated and characterized by differential hybridization of human fetal liver and human fetal brain cDNA libraries with total cDNA probes from different human tissues. The sequencing and analysis of nucleotide sequences indicated that the most isolated cDNA clones have contained unknown genes.