[Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)]. / Dinamika simptomov sindroma otmeny alkogolia v protsesse lecheniia nooklerinom (deanola atseglumat).

AIM: To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics. MATERIAL AND METHODS: A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35). RESULTS AND CONCLUSION: Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.