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BMJ Case Rep ; 20162016 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-27118753

RESUMO

We present a case of a 77-year-old man with a history of myeloproliferative disorder. He was admitted with a 2-week history of erythaema, swelling and significant pain of the right forearm following a mechanical fall at home, which had caused a skin laceration. During his admission, he developed ongoing intermittent fever and persistently elevated C reactive protein, and total white cell count. Initially, he was treated with antibiotics for suspected cellulitis. However, symptoms continued to progress, making a suitable management plan challenging. Wound swabs, blood cultures and viral PCR did not confirm infection. A punch biopsy of a skin lesion on the forearm was performed. The histology demonstrated a dense infiltrate of neutrophils and neutrophilic debris in keeping with acute febrile neutrophilic dermatosis (Sweet's syndrome). He was treated with oral steroids and after that he had a complete resolution of symptoms. However, he required a period of rehabilitation before returning home.


Assuntos
Janus Quinase 2/metabolismo , Transtornos Mieloproliferativos/complicações , Pele/patologia , Síndrome de Sweet/diagnóstico , Idoso , Biópsia , Humanos , Masculino , Transtornos Mieloproliferativos/metabolismo , Infiltração de Neutrófilos , Neutrófilos , Síndrome de Sweet/etiologia , Síndrome de Sweet/metabolismo , Síndrome de Sweet/patologia
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