RESUMO
160 specimens of composite (80 chemical and 80 light cured) were prepared in teflon mold 4 mm x 2.5 mm in dimension. Plaque samples were collected using absorbent paper points from 20 normal persons and 20 persons with cervical carious teeth. The samples were inoculated in TSB containing both types of composites. Duplicate cultures were done for aerobic and anaerobic incubations at 37 degrees C. There was no effect of both types of composite on the quality of the isolated organisms from normal group or patient group. Chemical and light cured composite increased significantly the count of aerobic bacterial plaque from normal group. While they decreased the count of aerobic bacterial plaque from patient group and also the anaerobic bacterial plaque from both normal and patient group.
Assuntos
Resinas Compostas/farmacologia , Placa Dentária/microbiologia , Adulto , Bactérias Aeróbias/efeitos dos fármacos , Bactérias Anaeróbias/efeitos dos fármacos , Técnicas Bacteriológicas , Contagem de Colônia Microbiana , Cárie Dentária/microbiologia , Feminino , Humanos , Técnicas In Vitro , MasculinoRESUMO
A newly developed 1% eye preparation of the potent antistaphylococcal antibiotic fusidic acid, showed an excellent clinical effect in 206 Egyptian children with external eye infections. The 248 patients included in the study were randomized, in the ratio 5:1, to either fusidic acid or chloramphenicol 0.5% eye drops. Both preparations were given four to six times daily for one week. Bacterial conjunctivitis was diagnosed in 56% of the children. Offending eye pathogens were mainly Staphylococcus aureus (60%), Haemophilus aegyptius (10%), Streptococcus pneumoniae (13%) and Neisseria gonorrhoeae (6%). The overall clinical success rate in children with bacterial conjunctivitis was 85% with fusidic acid, compared to 48% with chloramphenicol (p less than 0.001). The better effect of fusidic acid could be ascribed to a lower frequency of in vitro resistance (16%) in comparison to chloramphenicol (55%). Both drugs were apparently well tolerated and no side-effects were observed.
Assuntos
Conjuntivite Bacteriana/tratamento farmacológico , Ácido Fusídico/uso terapêutico , Adolescente , Bactérias/efeitos dos fármacos , Criança , Pré-Escolar , Cloranfenicol/uso terapêutico , Resistência Microbiana a Medicamentos , Feminino , Humanos , Masculino , Soluções OftálmicasRESUMO
A passive haemagglutination technique was used to measure the E. coli antibody response in children with acute and chronic urinary tract infections with or without renal involvement. The E. coli antibody titre was also determined in sera of control normal children. In acute infections with renal involvement there was markedly high antibody response whereas in acute infections without renal involvement the rise in the antibody response to E. coli was only slight. In patients with chronic pyelonephritis the titres were also markedly high. E. coli antigens from 3 different sources were used in an attempt to find a substitute antigen for cases with negative urinary cultures. The 3 antigens used were urinary strains (only in patients with positive urinary cultures), patient's faecal strain and a polyvalent standard E. coli antigen. The faecal antigens gave results similar to the urinary ones in only 52% while the polyvalent antigen was found to be a more valuable substitute antigen giving equal titres to those with the urinary antigens in about 63% of the cases.
