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Environ Sci Pollut Res Int ; 31(11): 17289-17298, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38340299

RESUMO

The present work explores the genotoxicity of the fungicides iprodione (IP) and tebuconazole (TB) using the Allium cepa assay as an in vivo biological model. Both short-term and long-term exposures were studied, revealing concentration- and time-dependent cytological and genotoxic effects. IP exhibited genotoxicity over a wider concentration range (5-50 µg/ml) and required 30 h of exposure, while TB showed genotoxicity at higher concentrations (10 and 30 µg/ml) within a 4-h exposure period. The study highlights the importance of assessing potential risks associated with fungicide exposure, including handling, disposal practices, and concerns regarding food residue. Moreover, the research underscores the genotoxic effects of IP and TB on plant cells and provides valuable insights into their concentration and time-response patterns.


Assuntos
Aminoimidazol Carboxamida/análogos & derivados , Fungicidas Industriais , Hidantoínas , Cebolas , Triazóis , Meristema , Fungicidas Industriais/toxicidade , Dano ao DNA , Raízes de Plantas , Aberrações Cromossômicas
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