RESUMO
Analyzing the phenotypic characterization of the immune system cells involved in the pathogenesis of immunodeficiency with thymoma (Good's syndrome) is difficult due to the low number of studies on that subject. We describe the immunological alterations observed in a case of Good's syndrome, and we summarize the pathogenic explanations found in the literature.
Assuntos
Contagem de Células Sanguíneas/métodos , Citometria de Fluxo/métodos , Síndromes de Imunodeficiência/sangue , Timoma/sangue , Humanos , Síndromes de Imunodeficiência/complicações , Síndromes de Imunodeficiência/cirurgia , Masculino , Pessoa de Meia-Idade , Timectomia/efeitos adversos , Timoma/complicações , Timoma/cirurgiaRESUMO
El cáncer de pulmón es una de las neoplasias más frecuentes. La clínica se debe al propio tumor, a su extensión o a los síndromes paraneoplásicos asociados. A pesar de que las metástasis de localización biliopancreática son frecuentes, la afectación en esta región como inicio de una neoplasia pulmonar, tanto en la forma de pancreatitis como en la de ictericia obstructiva, es rara. Exponemos nuestra experiencia clínica mediante la presentación de 2 casos de pancreatitis aguda y uno de ictericia obstructiva como forma de inicio de una neoplasia pulmonar avanzada junto con una breve revisión bibliográfica, que confirma la ausencia de protocolos de actuación en esta situación (AU)
Lung cancer is one of the most frequent neoplasms. The symptoms are due to the cancer itself, its extension, and associated paraneoplastic syndromes. Although biliopancreatic metastases are common, biliopancreatic involvement as the initial symptom of lung cancerwhether as pancreatitis or obstructive jaundiceis rare. We describe our clinical experience, reporting two patients with acute pancreatitis and one patient with obstructive jaundice as the clinical presentation of advanced lung cancer. We also provide a brief review that highlights the absence of guidelines in this situation (AU)
Assuntos
Humanos , Pancreatite Necrosante Aguda/complicações , Icterícia Obstrutiva/complicações , Neoplasias Pulmonares/patologia , Metástase Neoplásica/patologia , Carcinoma de Células Pequenas/patologiaRESUMO
Lung cancer is one of the most frequent neoplasms. The symptoms are due to the cancer itself, its extension, and associated paraneoplastic syndromes. Although biliopancreatic metastases are common, biliopancreatic involvement as the initial symptom of lung cancer--whether as pancreatitis or obstructive jaundice--is rare. We describe our clinical experience, reporting two patients with acute pancreatitis and one patient with obstructive jaundice as the clinical presentation of advanced lung cancer. We also provide a brief review that highlights the absence of guidelines in this situation.
