RESUMO
A case is reported of malignant melanoma presenting as a mass in the head of the pancreas producing obstructive jaundice. On MR imaging the mass displayed signal characteristics not typical of adenocarcinoma but instead exhibited a low signal on T2-weighted images and early phase dynamic enhancement, the combination of which should suggest the possibility of melanoma.
Assuntos
Colestase/etiologia , Imageamento por Ressonância Magnética , Melanoma/diagnóstico , Neoplasias Pancreáticas/diagnóstico , Adenocarcinoma/diagnóstico , Colangiopancreatografia Retrógrada Endoscópica , Meios de Contraste , Diagnóstico Diferencial , Feminino , Gadolínio DTPA , Humanos , Melanoma/complicações , Melanoma/cirurgia , Pessoa de Meia-Idade , Neoplasias Pancreáticas/complicações , Neoplasias Pancreáticas/cirurgia , StentsRESUMO
The impact of mycotoxins on human and animal health is now increasingly recognised. Mycotoxin entry to the human and animal dietary systems is mainly by ingestion but increasing evidence also points at entry by inhalation. Mycotoxins exhibit a wide array of biological effects and individual mycotoxins can be mutagenic, carcinogenic, embryotoxic, teratogenic, or oestrogenic. Average levels of ingestion of currently known mycotoxins in most EEC countries are rather low. Little is known about the consequences to humans of such mycotoxin intakes. Establishing a causal relationship between mycotoxin exposure and human disease is complicated by uncertainties associated with human epidemiological studies. Analysis of mycotoxin adducts in human populations can act as a surrogate for human genotoxicity. Mycotoxins can also be immunosuppressive and appear to involve cellular immune phenomena and non-specific humoral factors associated with immunity.
Assuntos
Micotoxinas/toxicidade , Animais , Microbiologia de Alimentos , Humanos , Sistema Imunitário/efeitos dos fármacosRESUMO
A chart audit was undertaken to ascertain the content and quality of documented information present in medical records of patients with traumatic injuries seen in a tertiary care hospital. Of the records of children younger than 6 years of age with a diagnosis of fracture, burn, contusion, or intracranial injury seen in the inpatient or outpatient services during a one-year period, 60% contained inadequate data on which to determine retrospectively if the medical diagnosis of child abuse was ever considered. The medicolegal implications of this are discussed.
Assuntos
Maus-Tratos Infantis , Anamnese , Ferimentos e Lesões/etiologia , Pré-Escolar , Humanos , Lactente , Recém-NascidoAssuntos
Maus-Tratos Infantis , Pessoas com Deficiência , Deficiência Intelectual/psicologia , Criança , Pré-Escolar , Humanos , Lactente , Recém-Nascido de Baixo Peso , Recém-Nascido , Deficiência Intelectual/etiologia , Relações Mãe-Filho , Risco , Isolamento Social , Estresse Psicológico , Ferimentos e Lesões/etiologiaAssuntos
Pessoas com Deficiência , Pais , Relações Profissional-Família , Adulto , Criança , Maus-Tratos Infantis , Pré-Escolar , Feminino , Humanos , Masculino , Relações Médico-Paciente , Estresse PsicológicoRESUMO
Infant motor development was studied in three socio-cultural groups inYucatan, Mexico, using the Denver Developmental Screening Test f9DDSTF0 AND THEBayley Infant Motor Scale. Eight infants f9four boys and four girlsf0 at each monthof age from two weeks to one year and two weeks were examined in each group, a total of 288infants f996 in each groupf0. There were no significant differences in motor developmentamong the groups or between boys and girls. There was an increase in abilities with age. Compared with the Bayley norms for the USA, fine motor co-ordination was advanced inthese children but there was a delay in walking. The DDST was unable to detect childrenmore than one standard deviation below the mean on the Bayley Infant Motor Scale.