Clinical efficacy of different side branch protection techniques on patients receiving coronary intervention and prognostic analysis.

OBJECTIVE: To investigate and analyze the clinical efficacy of different side branch protection techniques on patients receiving coronary intervention and the patient's prognosis. PATIENTS AND METHODS: A total of 80 patients with coronary heart disease treated in Jiangmen Central Hospital from January 2014 to January 2017 were collected. According to different side branch protection strategies selected during operation, they were divided into jailed wire technique (JWT) group (n=20), jailed balloon technique (JBT) group (n=20), balloon-stent kissing technique (BSKT) group (n=20), and BSKT+RW group (n=20). The relevant operation parameters and the prevalence of adverse reactions at 1 month and 6 months after operation were compared among the four groups. RESULTS: The success rate of operation and relevant operation parameters in BSKT+RW group were slightly superior to those in the other three groups, but there were no significant differences among the four groups (p>0.05). Besides, the prevalence rates of adverse reactions at 1 month and 6 months after the operation had no significant differences among the four groups, but they were slightly lower in BSKT+RW group than those in the other three groups. CONCLUSIONS: There are no significant differences in the clinical efficacy and postoperative recovery of patients receiving coronary intervention among the four kinds of different side branch protection techniques. However, BSKT+RW is slightly superior to the other three treatment methods, which, therefore, is a preferred choice if the patient's economic conditions permit.

[Clinical evaluation of HIV-1/2 antibody rapid tests.].

BACKGROUND: To evaluate the sensitivity and specificity of HIV-1/2 antibody rapid tests prior to licensing. METHODS: Four hundred forty, 264 and 300 blood samples were collected from normal blood donors, drug addicted individuals and HIV infected patients, respectively. All the samples were tested with 17 kinds of HIV-1/2 antibody rapid tests prior to licensing. The sensitivity and specificity of each test were calculated. RESULTS: The sensitivity for all evaluated rapid tests was 100% for detecting 300 strong positive samples for HIV antibody; the specificity for all evaluated rapid tests was within the range of 97.7%-100% for detecting 440 samples from normal blood donors; the sensitivity and specificity of all tests were within the range of 70.3%-95.1% and 59.1%-100% respectively for detecting 264 samples from HIV high risk population. CONCLUSION: The sensitivity and specificity of different tests were different and the samples from HIV high risk population may be very useful for evaluation of the quality of HIV-1/2 antibody rapid tests.

Jumonji, a nuclear protein that is necessary for normal heart development.

Jumonji (jmj) was cloned in a gene trap screen to identify and mutagenize genes important for heart development. To investigate the role of jmj in heart development, we generated mice homozygous for the jmj mutation. The jmj homozygous mouse embryos showed heart malformations, including ventricular septal defect, noncompaction of the ventricular wall, double-outlet right ventricle, and dilated atria. The jmj mutants died soon after birth, apparently as a result of respiratory insufficiency caused by rib and sternum defects in addition to the heart defects. In situ hybridization analyses suggested that cardiomyocytes were differentiated but developmental regulation of chamber-specific genes was defective in fetal hearts. Expression of jmj was detected in the myocardium, especially in the interventricular septum, ventricular wall, and outflow tract, which correlated well with the locations of defects observed in the hearts of mutant mice. Homozygous embryos failed to express the jmj transcript in all tissues except in the nervous system. Confocal microscopic examination using anti-JMJ antibodies indicated that the JMJ protein was localized in the nuclei of cells transfected with jmj. These data demonstrate that JMJ is a nuclear protein, which is essential for normal heart development and function.

Volatile infochemicals used in host and host habitat location byCotesia flavipes Cameron andCotesia sesamiae (Cameron) (Hymenoptera: Braconidae), larval parasitoids of stemborers on graminae.

FemaleCotesia flavipes Cameron andCotesia sesamiae (Cameron) were attracted to odors in a Y-tube olfactometer from uninfested maize (Zea mays L.), sorghum [Sorghum bicolor (L.)], and napier grass (Pennisetum purpureum Schumach). In dual choice tests,Cotesia flavipes showed a preference for maize over sorghum, while maize and napier grass were equally attractive. In contrast,Cotesia sesamiae preferred volatiles from sorghum and napier grass over those from maize. The two parasitoids were significantly more attracted to maize infested with the stemborers,Chilo partellus (Swinhoe),Chilo orichalcociliellus Strand,Sesamia calamistis Hampson, andBusseola fusca (Fuller), than uninfested maize. In dual choice tests,Cotesia flavipes andCotesia sesamiae were unable to discriminate between odors from plants infested by the different species of stemborers.