Asymptomatic bacteriuria in patients with type 2 diabetes mellitus in rural southwestern Nigeria: a cross-sectional study.

OBJECTIVES: We aimed to identify the prevalence, bacterial isolates, antimicrobial susceptibility profile, and factors associated with asymptomatic bacteriuria (ASB) in patients with type 2 diabetes mellitus (T2DM) in rural southwestern Nigeria. METHODS: We performed a hospital-based cross-sectional study of patients with T2DM and ASB. Demographic and clinical data were collected using questionnaires. Urine samples were cultured using standard laboratory procedures, and bacterial colonies were isolated and antimicrobial sensitivity was performed using the disc diffusion technique. Relationships between variables were assessed using adjusted odds ratios (AORs) and 95% confidence intervals (CIs). RESULTS: Of the 280 participants, 73 (26.1%) had ASB (95% CI: 20.9%-31.2%). The most commonly identified isolate was E. coli (45/73; 61.7%), 100.0% of which were sensitive to cefuroxime but resistant to ciprofloxacin. Female sex (AOR, 6.132; 95% CI: 2.327-16.157), living below the poverty line (AOR, 2.066; 95% CI: 1.059-4.029), uncontrolled blood glucose (AOR, 2.097; 95% CI: 1.000-4.404), and a history of indwelling urethral catheterization (AOR, 14.521; 95% CI: 4.914-42.908) were associated with ASB. CONCLUSION: The findings suggest that cefuroxime should be used as an empirical treatment, pending urine culture and sensitivity, and that efforts should be made to prevent ASB in rural southwestern Nigeria.

Quantification and health impact assessment of polycyclic aromatic hydrocarbons (PAHs) emissions from crop residue combustion.

Emission of Polycyclic Aromatic Hydrocarbon compounds from combustion of crop residue was investigated. Crop residues comprising maize cobs, maize husks, rice husks and bean chaff were burnt in a furnace at a temperature of 400 °C and the emissions from the combustion process were characterized using standard methods. Health risk through inhalation was assessed using toxic equivalent factors and excess lifetime cancer risk. The results showed the detection of 16 PAH compound which included: Benzo[ghi]perylene, Naphthalene, Acenaphthene, Anthracene, Phenanthrene, Fluorene, Fluoranthene, Acenaphthylene, Pyrene, Benzo[a]anthracene, Dibenzo[a,h]anthracene, Benzo[b]fluoranthene, Chrysene, Benzo[a]pyrene, Indene[1,2,3-cd]pyrene and Benzo[k]fluoranthene. Benzo[b]fluoranthene had highest mean concentration of 1.30 µg/mg while Dibenzo[a,h]anthracene had the lowest mean concentration of 0.01 µg/mg. It was also revealed that the toxicity of PAHs was due to the presence of Benzo[b]fluoranthene for all the samples except for sample 4 for which the main contribution to toxicity was emission from benzo(a)pyrene, while the cancer risk assessment estimated to be 1.2 × 10-1 was far above the acceptable carcinogenic risk limit of 1 × 10-6. This study concluded that, more efforts are needed to reduce emission of PAHs from the combustion of crop residues into the ambient air otherwise, human health could be under threat especially if exposed for a long period.

Indoor transmission dynamics of expired SARS-CoV-2 virus in a model African hospital ward.

Cough and sneeze droplets' interactions with indoor air of a typical hospital clinic that could be majorly found in developing African countries were studied to investigate the effectiveness of existing guidelines/protocols being adopted in the control of the widespread coronavirus disease (COVID-19) transmission. The influences of indoor air velocity, the type, size distribution, residence time in air, and trajectory of the droplets, were all considered while interrogating the effectiveness of physical distancing measures, the use of face covers, cautionary activities of the general public, and the plausibility of community spread of the SARS-CoV-2 virus through airborne transmission. Series of 3-D, coupled, discrete phase models (DPM) were implemented in the numerical studies. Based on DPM concentration maps as function of particle positions and particle residence times that were observed under different droplets release conditions, the virus-laden droplets could travel several meters away from the source of release (index patient), with smaller-sized particles staying longer in the air. The behavior of indoor air was also found to indicate complex dynamics as particle transports showed no linear dependence on air velocity. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40201-020-00606-5.

Air emissions and health risk assessment around abattoir facility.

The study assessed the impacts of abattoir activities on ambient air quality and health risk associated with exposure to PM2.5 and PM10, H2S, SO2 and NH3. Air samplings were done simultaneously around the abattoir at three points for sixty consecutive days (October to November) and standard methods adopted for the samplings and analysis. Health risks associated with exposure to PM10 and PM2.5 were estimated, using attributable fractions, relative risk and the excess lifetime cancer risk. The non-carcinogenic risks induced by the inhalation of H2S, SO2 and NH3 were also evaluated using hazard quotient (HQ). The results indicated that the average concentrations of 18.75 µg/m3, 89.17 µg/m3 and 0.1ppm for PM2.5, PM10 and NO2 respectively, were higher than the World Health Organization (WHO), National Ambient Air Quality Standard (NAAQS) and Federal Ministry of Environment (FMEnv) permissible limits. Air Quality Index showed that the ambient air quality in respect of CO and NH3 was very good, moderate for PM10 and was very poor for NO2 and SO2. It was also shown that 0.32% of deaths from lung cancer, and 0.23% from cardiopulmonary could be avoided if PM2.5 is reduced to 3 µg/m3 and while about 0.14% of all-cause mortality could be avoided if PM10 is reduced to 10 µg/m3. In similar manner, at least 0.45% likelihood that an individual in a group of people exposed to PM2.5 100m away from the burning point may have health issue (lung cancer) than an individual from another set of people that is exposed to baseline concentration of 3 µg/m3. All the HQ values exceeded the threshold value, set at the unity, implying that H2S, SO2 and NH3 are likely to cause adverse health effects in the area. Conclusively, continuous operation of this abattoir within the residential area can constitute a great environmental menace to the residents of the area and can result in complication to those with existing health challenge.

Landfill air and odour emissions from an integrated waste management facility.

A mixture of gases and obnoxious odours are major components of landfill emission. A dispersion modelling on air pollutants and odour emissions anticipated from a proposed Integrated Waste Management Facility was conducted considering five operating scenarios. Impacts of the predicted ground level concentrations of air pollutants (including carbon monoxide, CO; oxides of nitrogen, NOX; sulphur dioxide, SO2; particulate matter, PM and hydrocarbons, HC) and odour on ambient air quality were investigated using the 10-min 1 OU/m3 odour limit, CH4 Lower Explosive Limit (LEL) and the daily limits of CO, NOx, SO2, PM and HC. The anticipated maximum ground level concentration of emitted odour and CH4 are 0.0040 OU/m3 and 0.0349 ppm, respectively. Simultaneous operations of all the major components of the facility will generate the daily maximum concentrations of 7.34, 2.60, 7.31, 29.72 and 0.42 µg/m3, for CO, NOX, SO2, PM and HC, respectively. Generally, the facility impacts on ambient air quality will be within the acceptable limit.