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Ann Acad Med Singap ; 25(6): 837-41, 1996 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-9055013

RESUMO

Porokeratosis is a well-recognised disorder of keratinization with distinctive clinical features and histological hallmark of cornoid lamella. There are at least 4 different clinical variants, with malignant transformation reported in almost all types of porokeratosis. This is a retrospective study on all cases of porokeratosis seen at the National Skin Centre, Singapore from 1990 to 1993. There was a total of 31 patients diagnosed to have porokeratosis during the study period. They can be classified into 4 main clinical variants: (1) disseminated superficial actinic porokeratosis (41.9%), (2) classical porokeratosis of Mibelli (35.5%), (3) porokeratosis palmaris, plantaris et disseminatum (9.7%), and (4) linear porokeratosis (12.9%). Our typical patient is in his/her early forties, who noticed asymptomatic porokeratotis lesion on sun-exposed skin. Various treatment modalities were used, with no one method being more superior to another. None of our patients had malignant transformation of pre-existing skin lesions during the short follow-up period from less than one year to three years. Patients should be advised to avoid excessive sunlight, to use sunscreen and go for periodic examination by a dermatologist with a view to close skin malignancy surveillance.


Assuntos
Poroceratose/diagnóstico , Poroceratose/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Poroceratose/patologia , Poroceratose/terapia , Estudos Retrospectivos , Fatores de Risco , Distribuição por Sexo , Singapura/epidemiologia
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