Rapid immunoturbidimetric assay of albumin and immunoglobulin G in serum and cerebrospinal fluid with an automatic discrete analyser.

A method is presented to determine albumin and immunoglobulin G (IgG) in serum and cerebrospinal fluid (CSF) with an automatic discrete analyser. Concentrations of albumin and IgG in serum and CSF are compared with values obtained by radial immunodiffusion (RID). Ratios of albumin in CSF over albumin in serum and the so-called IgG index are calculated. Ratios obtained with the discrete analyser and with the RID are compared and discussed with respect to clinical diagnosis.