Catastrophic antiphospholipid syndrome: challenging case and importance of multidisciplinary evaluation and management.

Our case depicts a challenging diagnosis of catastrophic antiphospholipid syndrome in a young patient with a heterogenous presentation with extensive clinical course, a wide range of investigations, including multimodality imaging, and multidisciplinary expertise, to initiate prompt treatment addressing multiorgan thrombotic injury.

Dizziness and the Otolaryngology Point of View.

Dizziness can be due to pathology from multiple physiologic systems, the most common being vestibular. Dizziness may be categorized as vertigo, disequilibrium, lightheadedness, or oscillopsia. Vertigo is an illusion of motion often caused by asymmetrical vestibular input to the brainstem. To evaluate vertigo, it is essential to include the symptom's quality, timing, frequency, trigger, influence from positional changes, and other associations from the history. Oculomotor, otologic, balance testing, positional testing, and nystagmus testing are equally important components of the examination. Two of the most common diagnoses are readily treated with canalith repositioning maneuvers and vestibular rehabilitation exercises.

Exposure to an extreme environment comes at a sensorimotor cost.

Long duration space flight is known to induce severe modifications in the sensorimotor and musculoskeletal systems. While in-flight strategies including physical fitness have been used to prevent the loss of bone and muscle mass using appropriate rehabilitative countermeasures, less attention has been put forth in the design of technologies that can quickly and effectively assess sensorimotor function during missions in space. The aims of the present study were therefore (1) to develop a Portable Sensorimotor Assessment Platform (PSAP) to enable a crewmember to independently and quickly assess his/her sensorimotor function during the NASA's Extreme Environment Mission Operations (NEEMO) and (2) to investigate changes in performance of static posture, tandem gait, and lower limb ataxia due to exposure in an extreme environment. Our data reveal that measuring the degree of upper body balance and gait regularity during tandem walking using PSAP provided a sensitive and objective quantification of body movement abnormalities due to changes in sensorimotor performance over the duration of mission exposure.